DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKI and CG10177

DIOPT Version :9

Sequence 1:	NP_524622.1	Gene:	CaMKI / 43792	FlyBaseID:	FBgn0016126	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_651150.1	Gene:	CG10177 / 42772	FlyBaseID:	FBgn0039083	Length:	411	Species:	Drosophila melanogaster

Alignment Length:	288	Identity:	84/288 - (29%)
Similarity:	138/288 - (47%)	Gaps:	38/288 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 DSG--KKAKAKDLKELNKQVSIEE----KYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKK 66
            |||  :..|:.||.|. .|:.||.    ::|...|:..|   :.|...:|      ..||:::|:
  Fly   129 DSGTLESMKSHDLPEA-IQLYIETIEPVEHNTRTLIYRG---QTRANRTK------CTVKMVNKQ 183

  Fly    67 ALKGKEESLENEIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELF 131
            ...........|..|||:..              :||||::|:.|.||:..:|.|:|.:...  .
  Fly   184 TQSNDRGDTYMEAEVLRQLQ--------------SHPNIIELMYTVEDERYMYTVLEHLDCN--M 232

  Fly   132 DRIVEK-GSYTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPD---DDSKIMISDFGL 192
            .::::| |..:|.||..::|..:.|:.:||:..|:|||:||||||..|..   :...:.:::|.|
  Fly   233 QKVIQKRGILSEADARSVMRCTVSALAHMHQLQVIHRDIKPENLLVCSSSGKWNFKMVKVANFDL 297

  Fly   193 SKMEDSGIMATACGTPGYVAPEVLAQKPYGKAVDVWSIGVISYILLCGYPPFYD--ENDANLFAQ 255
            :.......:...||||.|:|||::|...|...||.||:||..:.:|||..||..  :|...::|.
  Fly   298 ATYYRGSKLYVRCGTPCYMAPEMIAMSGYDYQVDSWSLGVTLFYMLCGKMPFASACKNSKEIYAA 362

  Fly   256 ILKGDFEFDSPYWDEISESAKHFIKNLM 283
            |:.|...:.......:|..|...|..|:
  Fly   363 IMSGGPTYPKDMESVMSPEATQLIDGLL 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	76/267 (28%)
CaMKI	NP_524622.1	S_TKc	31..302	CDD:214567	74/259 (29%)
CG10177	NP_651150.1	DCX	18..108	CDD:214711
		S_TKc	164..409	CDD:214567	72/252 (29%)
		PKc_like	164..403	CDD:304357	72/252 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900