Protein Alignment CaMKI and Lkb1

DIOPT Version :9

• Sequence 1: NP_524622.1
• Gene: CaMKI / 43792
• FlyBaseID: FBgn0016126
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: NP_001163606.1
• Gene: Lkb1 / 41673
• FlyBaseID: FBgn0038167
• Length: 567
• Species: Drosophila melanogaster
• Alignment Length: 414
• Identity: 104/414 - (25%)
• Similarity: 187/414 - (45%)
• Gaps: 78/414 - (18%)

  Fly     4 FGKKDSGKKAKAKDL--KELNKQVSIEEKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKK 66
            |.:.||      :|:  ::..|.:.:..||.:..:||.|::.:|:.|.:.::.. ..||||:.|:
  Fly   149 FNRVDS------QDIIYQQKKKSIKMVGKYIMGDVLGEGSYGKVKEAMNSENLC-RLAVKILTKR 206

  Fly    67 ALK---GKEESLENEIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLETY--EDKSKVYLVMELVT 126
            .|:   ..|:::..||.:|:               :|.|.::|:|::..  |:|.|:|||||...
  Fly   207 KLRRIPNGEQNVTREIALLK---------------QLKHRHVVELVDVLYNEEKQKMYLVMEYCV 256

  Fly   127 GG--ELFDRIVEKGSYTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISD 189
            ||  |:.|...:| ......|....:|:::.::|:|...|:|:|:||.|||.   ..|..:.|||
  Fly   257 GGLQEMIDYQPDK-RMPLFQAHGYFKQLVDGLEYLHSCRVIHKDIKPGNLLL---SLDQTLKISD 317

  Fly   190 FGLSKMED----SGIMATACGTPGYVAPEVL-AQKPY-GKAVDVWSIGVISYILLCGYPPFYDEN 248
            ||:::..|    .....|..|:|.:..||:. ..:.: |..||:||.||..|.|..|..||..:|
  Fly   318 FGVAEQLDLFAPDDTCTTGQGSPAFQPPEIANGHETFAGFKVDIWSSGVTLYNLATGQYPFEGDN 382

  Fly   249 DANLFAQILKGDFEFDSPYW-DEISESAKHFIKNLMCVTVEKRYTCKQALGHAW----------- 301
            ...|...|.:|.:|  :|.| .|:.....:.|..::.....||.:.::.....|
  Fly   383 IYRLLENIGRGQWE--APAWLYEMDADFANLILGMLQADPSKRLSLQEIRHDTWFRSAPVKTGPP 445

  Fly   302 -----ISGNEASSRNI--------HGTVSEQL---KKNFAKSRWKQAYYAATVIRQMQRMALNSN 350
                 :.|::..:..:        :||..|.:   :.:..:...:||..||:.||..|
  Fly   446 IPIPPLKGDKYRNSTVIPYLEAYHYGTQEEDVYFTEHDVNQELARQAAAAASEIRAKQ------- 503

  Fly   351 SNANFDSSNSSNQDSTTPTAATGA 374
            |.|...:.::....||:..||:.:
  Fly   504 SAAALAACHTYEPPSTSAAAASNS 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	81/287 (28%)
		S_TKc	31..302	CDD:214567	81/300 (27%)
Lkb1	NP_001163606.1	S_TKc	172..435	CDD:214567	80/284 (28%)
		STKc_LKB1	178..435	CDD:271021	79/278 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452313
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930