DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKI and camkvb

DIOPT Version :9

Sequence 1:	NP_524622.1	Gene:	CaMKI / 43792	FlyBaseID:	FBgn0016126	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_956744.1	Gene:	camkvb / 393422	ZFINID:	ZDB-GENE-040426-1140	Length:	436	Species:	Danio rerio

Alignment Length:	406	Identity:	163/406 - (40%)
Similarity:	251/406 - (61%)	Gaps:	35/406 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPLFGKKDSGKKAKAKDLKELNKQVSIEEKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDK 65
            || ||....|:|      |:.|....|.:||:|..::.:..|.|:..|:.|::...:...|.:.|
Zfish     1 MP-FGCLKPGEK------KDYNSPTEITDKYDLGQIVKSEEFCEIFRAKDKNTLKMYTCKKFLKK 58

  Fly    66 KALKGKEESLENEIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGEL 130
            ...|.: ::.:|||.:|:               .:.||||:||::.||.:.:.||.:||.||.|:
Zfish    59 DGRKVR-KAAKNEIVILK---------------MVKHPNILQLVDVYETRKEYYLFLELATGREV 107

  Fly   131 FDRIVEKGSYTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSKM 195
            ||.|:::|.|:|:|.|::|||::|||.|:|...:|||:||.|||:||:....|||:||||.|:|:
Zfish   108 FDWILDQGYYSERDTSNVIRQVMEAVAYLHSLKIVHRNLKLENLVYYNRLKHSKIVISDFHLAKL 172

  Fly   196 EDSGIMATACGTPGYVAPEVLAQKPYGKAVDVWSIGVISYILLCGYPPFYDE--------NDANL 252
            | :|::...||||.|:||||:.::.||:.||.|::|||.||||.|.||||||        :|.||
Zfish   173 E-NGLIKEPCGTPEYLAPEVVGRQRYGRPVDCWALGVIMYILLSGNPPFYDEADDDDYENHDKNL 236

  Fly   253 FAQILKGDFEFDSPYWDEISESAKHFIKNLMCVTVEKRYTCKQALGHAWISGNEASSRNIHGTVS 317
            |.:||.||:|||||||||||:|||:.:..||.|..::|.|.::|:.|.|||||.||.:||...|.
Zfish   237 FRKILAGDYEFDSPYWDEISDSAKNLVSRLMEVDQDQRLTAQEAINHEWISGNAASDKNIKENVC 301

  Fly   318 EQLKKNFAKSRWKQAYYAATVIRQMQRMALNSNSNANFDSSNSSNQDSTTPTAATGAWTSNVLSS 382
            .|::|||||::||:|....|::::: |...|..:.|...::.::....:....|.||..:...:|
Zfish   302 AQIEKNFAKAKWKKAVRVTTMMKRL-RAPENQTAAATAPAAEAAAASPSEADPAAGAQETPQAAS 365

  Fly   383 QQSV--QSHAQEMNKS 396
            :.|.  .|.|:.::.|
Zfish   366 EASTAPSSTAESLSAS 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	124/281 (44%)
CaMKI	NP_524622.1	S_TKc	31..302	CDD:214567	122/278 (44%)
camkvb	NP_956744.1	STKc_CaMK_like	22..286	CDD:270990	123/280 (44%)
		S_TKc	24..286	CDD:214567	122/278 (44%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	328..436		10/54 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	1	1.000	-	-		FOG0000163
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24347
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X46
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.920