DRSC/TRiP Functional Genomics Resources

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Protein Alignment CaMKI and Mylk3

DIOPT Version :9

Sequence 1:NP_524622.1 Gene:CaMKI / 43792 FlyBaseID:FBgn0016126 Length:405 Species:Drosophila melanogaster
Sequence 2:NP_001104280.1 Gene:Mylk3 / 291926 RGDID:1305801 Length:786 Species:Rattus norvegicus


Alignment Length:328 Identity:112/328 - (34%)
Similarity:173/328 - (52%) Gaps:24/328 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly    23 KQVSIEEKYNL--HGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGKEESLENEIRVLRRF 85
            |...|...|.:  |.:||.|.|.:|.....: |.|...|.|||..|.:|.:|: ::|||.::   
  Rat   472 KDTLISTSYTVSQHEVLGGGRFGQVHRCTER-STGLALAAKIIKVKNIKDRED-VKNEINIM--- 531

  Fly    86 SANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFDRIV-EKGSYTEKDASHLI 149
                        .:|:|.|::||.:.:|.|:...|:||.|.||||||||. ||...||.|.....
  Rat   532 ------------NQLSHVNLIQLYDAFESKNSFTLIMEYVDGGELFDRITDEKYHLTELDVVLFT 584

  Fly   150 RQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLS-KMEDSGIMATACGTPGYVAP 213
            |||.|.|.|:|:..::|.||||||:|..| ....:|.|.||||: :.:....:....|||.::||
  Rat   585 RQICEGVHYLHQHYILHLDLKPENILCVS-QTGHQIKIIDFGLARRYKPREKLKVNFGTPEFLAP 648

  Fly   214 EVLAQKPYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKGDFEFDSPYWDEISESAKHF 278
            ||:..:......|:||:|||:|:||.|..||..|.||.....|:...::||:..:..:||.||.|
  Rat   649 EVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGETDAETMNFIVNCSWDFDADTFKGLSEEAKDF 713

  Fly   279 IKNLMCVTVEKRYTCKQALGHAWISG--NEASSRNIHGTVSEQLKKNFAKSRWKQAYYAATVIRQ 341
            :..|:......|.:..|.|.|.|::.  .:||..|:.......|:|..|:.:||:.::..|.:.:
  Rat   714 VSRLLVKEKSCRMSATQCLKHEWLNHLIAKASGSNVRLRSQLLLQKYMAQRKWKKHFHVVTAVNR 778

  Fly   342 MQR 344
            :::
  Rat   779 LRK 781

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CaMKINP_524622.1 STKc_CaMKI 27..301 CDD:270985 101/277 (36%)
S_TKc 31..302 CDD:214567 100/274 (36%)
Mylk3NP_001104280.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 233..258
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 279..315
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 333..443
STKc_MLCK3 477..737 CDD:271094 100/277 (36%)
S_TKc 485..737 CDD:214567 99/269 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0032
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.900

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