DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKI and Uhmk1

DIOPT Version :9

Sequence 1:	NP_524622.1	Gene:	CaMKI / 43792	FlyBaseID:	FBgn0016126	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_058989.1	Gene:	Uhmk1 / 246332	RGDID:	2968	Length:	419	Species:	Rattus norvegicus

Alignment Length:	232	Identity:	59/232 - (25%)
Similarity:	94/232 - (40%)	Gaps:	38/232 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 YNLHGLLGTGAFSEVRLAESKDSPG------EHFAVKIIDKKALKGKEESLENEIRVLRRFSANH 89
            :.:...||:|:.:.|.......:||      :.|........|....|.....|...|.:.. .|
  Rat    23 WQVQSRLGSGSSASVYRVRCCGTPGSPPGALKQFLPPGTTGAAASAAEYGFRKERAALEQLQ-GH 86

  Fly    90 FDGKCLNGTRLTH--PNIVQ---LLETYEDKSKVYLVMELVTGGELFDRIVEKGSYTEKDASHLI 149
            .:...|.|....|  ||:..   |||..:......||.....|..::  :::          |..
  Rat    87 RNIVTLYGVFTIHFSPNVPSRCLLLELLDVSVSELLVYSSHQGCSMW--MIQ----------HCA 139

  Fly   150 RQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSKMEDSGIMATACGTPGYVAPE 214
            |.:|||:.::|.:|.||.||||.|:|:.:.::..|::  ||||| .::.........|.||.|||
  Rat   140 RDVLEALAFLHHEGYVHADLKPRNILWSAENECFKLI--DFGLS-FKEGNQDVKYIQTDGYRAPE 201

  Fly   215 VLAQKPYGK-----------AVDVWSIGVISYILLCG 240
            ...|....:           |||:||:|:|...:..|
  Rat   202 AELQNCLAQAGLQSDTECTSAVDLWSLGIILLEMFSG 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	59/232 (25%)
CaMKI	NP_524622.1	S_TKc	31..302	CDD:214567	59/232 (25%)
Uhmk1	NP_058989.1	STKc_KIS	22..308	CDD:270922	59/232 (25%)
Uhmk1	NP_058989.1	RRM_UHMK1	318..405	CDD:409898
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900