Protein Alignment CaMKI and Dclk3

DIOPT Version :10

• Sequence 1: NP_524622.1
• Gene: CaMKI / 43792
• FlyBaseID: FBgn0016126
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: NP_766516.2
• Gene: Dclk3 / 245038
• MGIID: 3039580
• Length: 790
• Species: Mus musculus
• Alignment Length: 300
• Identity: 129/300 - (43%)
• Similarity: 195/300 - (65%)
• Gaps: 24/300 - (8%)

  Fly     6 KKDSGKKAKAKDLKELNKQVSIEEKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKG 70
            ::.||:|.:.|.:    ....:|:.|::.|::|.|.|:.|:....:::. :.:|:|:|||..|||
Mouse   493 ERPSGRKPRPKGI----ISADVEKHYDIGGVIGDGNFATVKECRHRETK-QAYAMKMIDKSQLKG 552

  Fly    71 KEESLENEIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFDRIV 135
            ||:.:::||.:::               .|:|||||:|.|.||.::::||:||.|.||:|||.||
Mouse   553 KEDIVDSEILIIQ---------------SLSHPNIVKLHEVYETEAEIYLIMEYVQGGDLFDAIV 602

  Fly   136 EKGSYTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDS-KIMISDFGLSKMEDSG 199
            |...:.|.:|:.:|..:.:|:.:||::.:||||:||||||....:|.| .:.::||||:|.....
Mouse   603 ENVKFPEPEAAVMITDLCKALVHMHDKNIVHRDVKPENLLVQRNEDKSITLKLADFGLAKYVVRP 667

  Fly   200 IMATACGTPGYVAPEVLAQKPYGKAVDVWSIGVISYILLCGYPPFYD-ENDAN-LFAQILKGDFE 262
            |. |.||||.|||||:|::|.||..||:|:.|||.||||||:|||.. |.|.: ||..|..|.||
Mouse   668 IF-TVCGTPTYVAPEILSEKGYGLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQVGQFE 731

  Fly   263 FDSPYWDEISESAKHFIKNLMCVTVEKRYTCKQALGHAWI 302
            |.|||||.||::||..::||:.|..:||||.:|.|.|.||
Mouse   732 FLSPYWDNISDAAKDLVRNLLEVDPKKRYTAEQVLQHPWI 771

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	123/276 (45%)
Dclk3	NP_766516.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..37
		DCX_DCLK3	95..179	CDD:340528
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	201..290
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	315..506		4/16 (25%)
		Protein Kinases, catalytic domain	513..770	CDD:473864	122/273 (45%)