Protein Alignment CaMKI and chk-2

DIOPT Version :10

• Sequence 1: NP_524622.1
• Gene: CaMKI / 43792
• FlyBaseID: FBgn0016126
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: NP_001024271.1
• Gene: chk-2 / 180304
• WormBaseID: WBGene00000499
• Length: 476
• Species: Caenorhabditis elegans
• Alignment Length: 301
• Identity: 91/301 - (30%)
• Similarity: 148/301 - (49%)
• Gaps: 44/301 - (14%)

  Fly    19 KELNKQVSIEEKYNL--HGLLGTGAFSEVRLAESKDSPGEHFAVKIID-------KKALKGKEES 74
            :||.|      ||::  |. ||.|.|.:|.|...| |.....|:|.::       .:|: .|...
 Worm   163 EELTK------KYHVTSHS-LGKGGFGKVLLGYKK-SDRSVVAIKQLNTQFSTRCSRAI-AKTRD 218

  Fly    75 LENEIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFDRIVEKGS 139
            :.||:.|::               :|:|||||.:.:........|:|:|.|.|||.|.::|: ..
 Worm   219 IRNEVEVMK---------------KLSHPNIVAIYDWITVAKYSYMVIEYVGGGEFFSKVVD-SK 267

  Fly   140 YT-----EKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSKMEDSG 199
            |.     |....:...|:::|:.|:|..|:.|||:||||:|.....:...:.::|||::| ....
 Worm   268 YNRMGLGESLGKYFAFQLIDAILYLHSVGICHRDIKPENILCSDKAERCILKLTDFGMAK-NSVN 331

  Fly   200 IMATACGTPGYVAPEVLAQK--PYGKAVDVWSIGVISYILLCGYPPFYDE-NDANLFAQILKGDF 261
            .|.|.||||.|.|||::|.:  .|...||:||:|.:.:|...|||||.:| .|..:..|:|.|..
 Worm   332 RMKTRCGTPSYNAPEIVANEGVEYTPKVDIWSLGCVLFITFSGYPPFSEEYTDMTMDEQVLTGRL 396

  Fly   262 EFDSPYWDEISESAKHFIKNLMCVTVEKRYTCKQALGHAWI 302
            .|.: .|..|:...::.||.::.|....|.:..:.:...|:
 Worm   397 IFHA-QWRRITVETQNMIKWMLTVEPSNRPSAVELMSTQWM 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	87/290 (30%)
chk-2	NP_001024271.1	FHA_CHK2	46..156	CDD:438718
		STKc_Chk2	162..436	CDD:270986	90/299 (30%)