DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKI and zyg-8

DIOPT Version :9

Sequence 1:	NP_524622.1	Gene:	CaMKI / 43792	FlyBaseID:	FBgn0016126	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_499571.2	Gene:	zyg-8 / 176639	WormBaseID:	WBGene00006993	Length:	802	Species:	Caenorhabditis elegans

Alignment Length:	283	Identity:	101/283 - (35%)
Similarity:	164/283 - (57%)	Gaps:	24/283 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 IEEKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGKEESLENEIRVLRRFSANHFD 91
            ::||:.|..|:|.|..:.|.....|.:..:..|:|:|.::.:.|||..:|.|:.:|:
Worm   478 LDEKFQLVRLIGDGNTAVVYEVIDKTNNDDRKAMKVIARENVIGKEHLIEMELAILQ-------- 534

  Fly    92 GKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFD--RIVEKGSYTEKDASHLIRQILE 154
                   ::.|..||||.:.:......||.:||:..|:||:  |||.:  ..|:||..::..:.:
Worm   535 -------KIDHTFIVQLYDHWFVDDSYYLSLELIEMGDLFEHLRIVRR--VPERDAVRMMTCLGQ 590

  Fly   155 AVDYMHEQGVVHRDLKPENLLYYSPD-DDSKIMISDFGLS--KMEDSGIMATACGTPGYVAPEVL 216
            |::|:||.|:||||:|.||||....: .:..:.::||||:  ..:|.|:::|.||||.|||||||
Worm   591 ALEYIHELGIVHRDVKLENLLIVKDEFGELGVKLADFGLAAEMPKDFGVLSTICGTPTYVAPEVL 655

  Fly   217 AQKPYGKAVDVWSIGVISYILLCGYPPFY--DENDANLFAQILKGDFEFDSPYWDEISESAKHFI 279
            .:..||..||:|:.|||.|.:|.|:|||.  |.::.:||:.|:.|:|.|.||.||::|.|.:|.|
Worm   656 NKTGYGCKVDIWAAGVILYAILVGFPPFQSSDGSEQDLFSAIMSGEFSFPSPSWDDVSWSVRHLI 720

  Fly   280 KNLMCVTVEKRYTCKQALGHAWI 302
            ..|:......||:..:.|...|:
Worm   721 MCLIHTDPFHRYSAGELLNDEWM 743

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	100/280 (36%)
CaMKI	NP_524622.1	S_TKc	31..302	CDD:214567	98/277 (35%)
zyg-8	NP_499571.2	DCX	206..298	CDD:214711
		DCX	335..423	CDD:214711
		STKc_DCKL	481..742	CDD:270997	99/277 (36%)
		S_TKc	482..743	CDD:214567	98/277 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820