Protein Alignment CaMKI and mnk-1

DIOPT Version :9

• Sequence 1: NP_524622.1
• Gene: CaMKI / 43792
• FlyBaseID: FBgn0016126
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: NP_871924.2
• Gene: mnk-1 / 174623
• WormBaseID: WBGene00011304
• Length: 707
• Species: Caenorhabditis elegans
• Alignment Length: 458
• Identity: 131/458 - (28%)
• Similarity: 211/458 - (46%)
• Gaps: 86/458 - (18%)

  Fly     1 MPLFG-----KKDSGKKAKAK----DLKELNKQVSIEEKYNLHGLLGTGAFSEVRLAESKDSPGE 56
            :||.|     .:..|:|..:|    |..:|..:         |  ||:||:..|...:|..| |.
 Worm   175 LPLGGGTRRVPRTPGRKNSSKCGFFDYYKLTDE---------H--LGSGAYGSVTTCKSIKS-GV 227

  Fly    57 HFAVKIIDKKALKGKEESLENEIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLV 121
            .:||||:||:......:.:..|:.:.:              |...||||||||:.:||::..|||
 Worm   228 EYAVKIVDKQGETHSRKRILREVNIFK--------------TCKDHPNIVQLLDWFEDETNFYLV 278

  Fly   122 MELVTGGELFDRIVEKGSYTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIM 186
            ||.:.||.|...|:::..:||::|..:.:.|..|:.:||::|:.|||:||||:|...|:..|.:.
 Worm   279 MEKMRGGPLLQHILQRKYFTEEEARRVTKDISLALKFMHDRGIAHRDVKPENVLCTDPNHVSPVK 343

  Fly   187 ISDFG-------------LSKMEDSGIMATACGTPGYVAPEVL-----AQKPYGKAVDVWSIGVI 233
            :.|..             ||::.....:|:..|:..::||||:     ....|.|..|.||:|||
 Worm   344 LCDLDLASQRPPQHERHPLSQVASEPDLASPVGSAEFMAPEVVDAYVGDSLKYDKKCDTWSLGVI 408

  Fly   234 SYILLCGYPPFY---DENDA-------------NLFAQILKGDFEFDSPYWDEISESAKHFIKNL 282
            .||:|.||.||.   |:.|.             :||.:|..|.:||....|..|||.||..:.||
 Worm   409 LYIMLAGYAPFQGMCDDEDCGWSEGKPCEDCQQDLFHRIQDGYYEFPEEEWGMISEEAKDLVSNL 473

  Fly   283 MCVTVEKRYTCKQALGHAWISGNEASSRNIHGTVSEQLKKNFAKSRWKQAYYAATVIRQMQRMAL 347
            :......|:...|.|.|.|:..:.||:  |..|.|..:.:   |...:.....:.....|.|:|
 Worm   474 LKRDPVDRFNADQILSHRWLQQSAAST--ILQTPSNLINR---KDSARDVQQMSEHFNLMNRLA- 532

  Fly   348 NSNSNANFDSSNSSNQDSTTPTAAT----GAWTS------NVLSSQQSVQSHAQEMNKSGGSTNA 402
            ::..:|.||:..:.::..:....||    |::.|      .....::|| ..|.|.::||..|..
 Worm   533 DTRLSARFDNKMTMSECGSDLGTATIHGDGSFLSMGGEPFGTFPRKKSV-GIAIEKSRSGEFTPP 596

  Fly   403 ASQ 405
            .|:
 Worm   597 ISR 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	98/307 (32%)
		S_TKc	31..302	CDD:214567	98/304 (32%)
mnk-1	NP_871924.2	PKc_like	200..492	CDD:328722	100/317 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920