Protein Alignment CaMKI and mak-1

DIOPT Version :10

• Sequence 1: NP_524622.1
• Gene: CaMKI / 43792
• FlyBaseID: FBgn0016126
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: NP_495860.1
• Gene: mak-1 / 174398
• WormBaseID: WBGene00010681
• Length: 521
• Species: Caenorhabditis elegans
• Alignment Length: 295
• Identity: 96/295 - (32%)
• Similarity: 146/295 - (49%)
• Gaps: 37/295 - (12%)

  Fly    24 QVSIEEKYNLHG-LLGTGAFSEVRLAESKDSPGEHFAVKII--DKKALKGKEESLENEIRVLRRF 85
            |..|.|.|.:.. ::|.|...:|.....|.: ||.||:|::  .:||.:      |.|:..|..
 Worm   136 QHQITEDYTISAEIIGIGESGKVMACYQKVT-GEKFALKVLRDSQKARR------EVELHWLTN- 192

  Fly    86 SANHFDGKCLNGTRLTHPNIVQLLETYE---DKSK-VYLVMELVTGGELFDRIVEKGS--YTEKD 144
                           .|.|:|.:|:.||   |..| :.:|:|.:.||:|..:...:||  ||||.
 Worm   193 ---------------AHENVVSILDIYENTFDNVKCLLMVVEFLEGGDLLSQFESQGSIPYTEKK 242

  Fly   145 ASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSKM-EDSGIMATACGTP 208
            ...:||||..||.|:|:..:.|||:|.||:|.....|:....:.|:|.:|. |.:.:|.:.|.||
 Worm   243 VGEIIRQIGNAVMYLHDMNIAHRDIKLENILCSGTGDNCVYKLGDYGFAKRPERNVLMESPCCTP 307

  Fly   209 GYVAPEVLAQKPYGKAVDVWSIGVISYILLCGYPPFYDENDANLF----AQILKGDFEFDSPYWD 269
            .|..||||.::.|.|:.|:||:||..|||||||||||......|.    ::|....:.|....||
 Worm   308 FYAPPEVLGRERYDKSCDMWSLGVAMYILLCGYPPFYSMKGVALSPGMRSRIANAYYAFPHEEWD 372

  Fly   270 EISESAKHFIKNLMCVTVEKRYTCKQALGHAWISG 304
            .:|:..|..|:.|:......|.|..:.:....::|
 Worm   373 CVSKDTKDDIRCLLRTNPSDRLTIHELMATPLVTG 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	94/287 (33%)
mak-1	NP_495860.1	STKc_MAPKAPK	142..403	CDD:270991	92/283 (33%)