Protein Alignment CaMKI and Speg

DIOPT Version :9

• Sequence 1: NP_524622.1
• Gene: CaMKI / 43792
• FlyBaseID: FBgn0016126
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: XP_011236945.1
• Gene: Speg / 11790
• MGIID: 109282
• Length: 3272
• Species: Mus musculus
• Alignment Length: 450
• Identity: 118/450 - (26%)
• Similarity: 191/450 - (42%)
• Gaps: 93/450 - (20%)

  Fly     9 SGKKAKAKDLKELNKQVSIE----------------EKYNLHGLLGTGAFSEVRLAESKDSPGEH 57
            :|:.:...:|..|:.|.::|                :.|::|..:|.||||.:|....:.| |..
Mouse  1578 AGEVSCKAELSVLSAQTAMEVEGVGEDEEHRGRRLSDYYDIHQEIGRGAFSYLRRVVERSS-GLE 1641

  Fly    58 FAVKIIDKKALKGKEESLENEIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVM 122
            ||.|.|..:| |.| .|...|.|:|               .||.|..::...|.:|.:..:.:|.
Mouse  1642 FAAKFIPSQA-KPK-ASARREARLL---------------ARLQHGCVLYFHEAFERRRGLVIVT 1689

  Fly   123 ELVTGGELFDRIVEKGSYTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYY-SPDDDSKIM 186
            ||.| .||.:|:..|.:..|.:....:||:||.:.|:|:..|:|.|:||||||.: ....:.::.
Mouse  1690 ELCT-EELLERMARKPTVCESETRTYMRQVLEGICYLHQSHVLHLDVKPENLLVWDGAGGEEQVR 1753

  Fly   187 ISDFGLSKMEDSGIMATAC--GTPGYVAPEVLAQKPYGKAVDVWSIGVISYILLCGYPPFYDEND 249
            |.|||.::....| ....|  |||.:||||::.|.|.....|:|.:||::::.|.|..||..|||
Mouse  1754 ICDFGNAQELTPG-EPQYCQYGTPEFVAPEIVNQSPVSGVTDIWPVGVVAFLCLTGISPFVGEND 1817

  Fly   250 ANLFAQILKGDFEFDSPYWDEISESAKHFIKNLMCVTVEKRY--TCKQALGHAWISGNEASSRNI 312
            ......|...:..|:...:..:|..|:.|   |:.|.|:.|.  |.::.|.|.|.. .||....:
Mouse  1818 RTTLMNIRNYNVAFEETTFLSLSREARGF---LIKVLVQDRLRPTAEETLEHPWFK-TEAKGAEV 1878

  Fly   313 HGTVSEQLKKNFAKSRWKQ---AYYAATVIRQMQRM--------------------ALNSNSNA- 353
            .   ::.||...::.||::   :|....|:|.:..:                    .|:|:|::
Mouse  1879 S---TDHLKLFLSRRRWQRSQISYKCHLVLRPIPELLRAPPERVWVAMPRRQPPSGGLSSSSDSE 1940

  Fly   354 ----------------NFDSSNSS-----NQDSTTPTAATGAWTSNVLSSQQSVQSHAQE 392
                            .|..|..|     .:|....|...||.|......|:...|..||
Mouse  1941 EEELEELPSVPRPLQPEFSGSRVSLTDIPTEDEALGTPEAGAATPMDWQEQERTPSKDQE 2000

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	89/294 (30%)
		S_TKc	31..302	CDD:214567	88/275 (32%)
Speg	XP_011236945.1	I-set	45..127	CDD:369462
		PHA03247	<320..697	CDD:223021
		I-set	737..826	CDD:369462
		SPEG_u2	827..883	CDD:293256
		I-set	884..974	CDD:369462
		Ig	988..1073	CDD:386229
		I-set	1079..1168	CDD:369462
		I-set	1203..1292	CDD:369462
		FN3	1297..>1374	CDD:238020
		I-set	1500..1589	CDD:369462	2/10 (20%)
		STKc_SPEG_rpt1	1613..1869	CDD:271010	88/278 (32%)
		PHA03247	<1951..2355	CDD:223021	11/49 (22%)
		PHA03307	2235..>2557	CDD:223039
		I-set	2597..2687	CDD:369462
		FN3	2691..2777	CDD:238020
		PHA03247	<2760..2981	CDD:223021
		STKc_SPEG_rpt2	2967..3223	CDD:271013

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900