DRSC/TRiP Functional Genomics Resources

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Protein Alignment CaMKI and Camk2d

DIOPT Version :9

Sequence 1:NP_524622.1 Gene:CaMKI / 43792 FlyBaseID:FBgn0016126 Length:405 Species:Drosophila melanogaster
Sequence 2:NP_001333564.1 Gene:Camk2d / 108058 MGIID:1341265 Length:533 Species:Mus musculus


Alignment Length:396 Identity:147/396 - (37%)
Similarity:204/396 - (51%) Gaps:50/396 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 EKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGKE-ESLENEIRVLRRFSANHFDG 92
            ::|.|...||.||||.||.. .|...|:.:|.|||:.|.|..:: :.||.|.|:.|         
Mouse    12 DEYQLFEELGKGAFSVVRRC-MKIPTGQEYAAKIINTKKLSARDHQKLEREARICR--------- 66

  Fly    93 KCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFDRIVEKGSYTEKDASHLIRQILEAVD 157
                  .|.|||||:|.::..::...|||.:||||||||:.||.:..|:|.||||.|:||||:|:
Mouse    67 ------LLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVN 125

  Fly   158 YMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSKMEDSGIMAT---ACGTPGYVAPEVLAQK 219
            :.|..|:|||||||||||..|....:.:.::||||: :|..|....   ..|||||::||||.:.
Mouse   126 HCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLA-IEVQGDQQAWFGFAGTPGYLSPEVLRKD 189

  Fly   220 PYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKGDFEFDSPYWDEISESAKHFIKNLMC 284
            ||||.||:|:.|||.||||.|||||:||:...|:.||..|.::|.||.||.::..||..|..::.
Mouse   190 PYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLT 254

  Fly   285 VTVEKRYTCKQALGHAWISGNEASSRNIHGTVSEQLKKNFAKSRWKQAYYAATVIRQMQRMALNS 349
            :...||.|..:||.|.||......:..:|...:....|.|...|..:.....|::......|..|
Mouse   255 INPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSAAKS 319

  Fly   350 ----------NSNANFDSSNSSNQDSTTPTAATGAWT---------------SNVLSSQQSVQSH 389
                      |:.||..:|...|    .||.|....|               ||.....:.|::.
Mouse   320 LLKKPDGVKINNKANVVTSPKEN----IPTPALEPQTTVIHNPDGNKESTESSNTTIEDEDVKAR 380

  Fly   390 AQEMNK 395
            .||:.|
Mouse   381 KQEIIK 386

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CaMKINP_524622.1 STKc_CaMKI 27..301 CDD:270985 123/275 (45%)
S_TKc 31..302 CDD:214567 123/274 (45%)
Camk2dNP_001333564.1 STKc_CaMKII 12..303 CDD:270988 129/307 (42%)
CaMKII_AD 380..507 CDD:285524 3/7 (43%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D330091at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X46
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.920

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