DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKI and camk4

DIOPT Version :9

Sequence 1:	NP_524622.1	Gene:	CaMKI / 43792	FlyBaseID:	FBgn0016126	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	XP_002943358.3	Gene:	camk4 / 100490912	XenbaseID:	XB-GENE-5911781	Length:	388	Species:	Xenopus tropicalis

Alignment Length:	401	Identity:	164/401 - (40%)
Similarity:	233/401 - (58%)	Gaps:	54/401 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 SGKKAKAKDLKELNKQVSIEEKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKI----IDKKALK 69
            ||..|....:...||. ::...|.|...||.||.|.|.....|.:. ..:|||:    :|||.::
Frog    32 SGSAAPEYWIDGSNKD-TLAHYYELESELGRGATSVVYRCRQKGTQ-RPYAVKMLKKTVDKKIVR 94

  Fly    70 GKEESLENEIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFDRI 134
                   .||.||               .||:||||::|.|.:|..:::.||:||||||||||||
Frog    95 -------TEIGVL---------------LRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRI 137

  Fly   135 VEKGSYTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSKMEDSG 199
            ||||.|:|:||:..::||||||.|:||.|:||||||||||||.:|..|:.:.|:||||||:.|..
Frog   138 VEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVDDQ 202

  Fly   200 I-MATACGTPGYVAPEVLAQKPYGKAVDVWSIGVISYILLCGYPPFYDE-NDANLFAQILKGDFE 262
            : |.|.||||||.|||:|....||..||:||:|:|:||||||:.||||| .|..:|.:||..|::
Frog   203 VTMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQYMFKRILNCDYD 267

  Fly   263 FDSPYWDEISESAKHFIKNLMCVTVEKRYTCKQALGHAWISGNEASSRNIHGTVSEQLKKNFAKS 327
            |.||:||::|.:||..:|.|:....:||.|.:|||.|.|::|..|:..:: ....::|::..|:.
Frog   268 FVSPWWDDVSLNAKDLVKKLIVFDPKKRLTTQQALQHPWVTGKAANFAHM-DNAQKKLQEFNARR 331

  Fly   328 RWKQAYYAATVIRQMQRMALNSNSNANFDSSNSSNQDSTTPTAATGAWTSNVLSSQQSV--QSHA 390
            :.|.|..|.        :|.:...:|...||:.||:.|..|:..           |:||  ::..
Frog   332 KLKAAVKAV--------VASSRLGSAGSHSSHDSNKPSRNPSPV-----------QESVCEETPT 377

  Fly   391 QEMN--KSGGS 399
            ||..  :.|||
Frog   378 QETKQVEEGGS 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	135/279 (48%)
CaMKI	NP_524622.1	S_TKc	31..302	CDD:214567	135/276 (49%)
camk4	XP_002943358.3	STKc_CaMKIV	49..342	CDD:270987	143/324 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	1	1.000	-	-		FOG0000163
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X46
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010