DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKI and dclk3

DIOPT Version :9

Sequence 1:	NP_524622.1	Gene:	CaMKI / 43792	FlyBaseID:	FBgn0016126	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	XP_009292709.1	Gene:	dclk3 / 100333376	ZFINID:	ZDB-GENE-081104-224	Length:	721	Species:	Danio rerio

Alignment Length:	428	Identity:	140/428 - (32%)
Similarity:	215/428 - (50%)	Gaps:	69/428 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PLFGKKDSGK-------KAKAKDLK-----ELNKQVS------------------IEEKYNLHGL 36
            |:..||.:.|       ..:.:||:     :.|||.:                  ||..|.:..:
Zfish   285 PIRPKKTAEKLTANNKSAPQTQDLETISEHDANKQETVLKDDNVPPDGAEVSLEDIERCYIMGRV 349

  Fly    37 LGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGKEESLENEIRVLRRFSANHFDGKCLNGTRLT 101
            :|.|.|:.||....:... |.||:||:|...|:|:...::|||.:||               .|.
Zfish   350 VGDGNFAVVRECRVRGLT-ETFAMKIVDNAKLQGRGHMVQNEIALLR---------------SLE 398

  Fly   102 HPNIVQLLETYEDKSKVYLVMELVTGGELFDRIVEKGSYTEKDASHLIRQILEAVDYMHEQGVVH 166
            ||.::||..::...:.|||:||||:||:|||.|.:.|.:||..|:.::|.|.:|::|:|::.:.|
Zfish   399 HPRLIQLFRSHHTDTHVYLLMELVSGGDLFDAITQSGRFTEPSAACMVRDISQALEYIHDKSIAH 463

  Fly   167 RDLKPENLLYYSPDDDS-KIMISDFGLSKMEDSGIMATACGTPGYVAPEVLAQKPYGKAVDVWSI 230
            ||:||||||.....:.| .:.::||||:.:....:. |.||||.|||||:||:..||..||||::
Zfish   464 RDIKPENLLVQRHGNGSLNLKLADFGLALVVKEPVF-TVCGTPTYVAPEILAETGYGVGVDVWAM 527

  Fly   231 GVISYILLCGYPPFY--DENDANLFAQILKGDFEFDSPYWDEISESAKHFIKNLMCVTVEKRYTC 293
            |||.::||.|:|||.  |.|...||..|.||:..|.|||||.:||.||..:::|:.|..:||.|.
Zfish   528 GVILFVLLSGFPPFRSPDRNQEELFRLIQKGEVHFLSPYWDNVSEGAKALVRSLLEVNPKKRLTA 592

  Fly   294 KQALGHAWISGNEASSRNIH-----GTVSEQLKKNFAKSRWKQAYYAATVIRQMQRMALNSNSNA 353
            .|.|...||  ..|:::..|     .|.|...::|..|           :.||::......:|..
Zfish   593 SQTLQDDWI--QHATTQKDHKGAIKATDSTAERRNQHK-----------LSRQVENAESTKHSPV 644

  Fly   354 NFDSSNSSNQDSTTPTAATGAWTSNVLSSQQSVQSHAQ 391
            .|.::.........|...| ...:..:....|:||..|
Zfish   645 TFHTAQIHENSKCVPDINT-TDRNQQIQETHSIQSKQQ 681

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	113/276 (41%)
CaMKI	NP_524622.1	S_TKc	31..302	CDD:214567	111/273 (41%)
dclk3	XP_009292709.1	UBQ	84..>156	CDD:294102
		STKc_DCKL	343..600	CDD:270997	111/273 (41%)
		S_TKc	344..601	CDD:214567	111/273 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920