DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lgs and pygo1

DIOPT Version :9

Sequence 1:	NP_651922.1	Gene:	lgs / 43791	FlyBaseID:	FBgn0039907	Length:	1469	Species:	Drosophila melanogaster
Sequence 2:	NP_001107109.1	Gene:	pygo1 / 797729	ZFINID:	ZDB-GENE-080204-62	Length:	337	Species:	Danio rerio

Alignment Length:	329	Identity:	76/329 - (23%)
Similarity:	114/329 - (34%)	Gaps:	103/329 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   814 GTGSLSGSV-PQANTSTVQAGTTTVLSANKNCFQADTPSPSNQNRSRNTGSSSVLTHNLSSNPST 877
            |.|.|.||. .:...|:.||...:.||.     .|..|:||             ..|.:::||..
Zfish    27 GPGLLLGSPDKKRRKSSTQAPPFSPLSE-----YAPPPNPS-------------ADHLIAANPFD 73

  Fly   878 PLSHLSPKEFESFGQS---SAGDNMKSRRPSPQG---QRSPVNSLIEANKDVRFAASSPGFNPHP 936
            . :::||.....||.|   ::.....||.|||.|   |..|          ..|:.:..||: ..
Zfish    74 D-NYISPSLKPYFGHSHYPASNSYGSSRMPSPYGPTIQTQP----------QYFSQNPTGFS-RT 126

  Fly   937 HMQSNSNSALNAYKMGSTNIQMERQASAQGGSVQFSRRSDNIP---LNPNSGNRPPPNKMTQNFD 998
            |..:.|.:.::|:..||.|     ..:...|||:   ..|.||   ||..|....|....|:|..
Zfish   127 HRFNYSPNYVHAFCGGSNN-----NNNMHFGSVE---HGDQIPLQNLNQRSPGFNPDANTTRNMS 183

  Fly   999 PISSLAQMSQQLTSCVSSMGSPAGTGGMTMMGGPGPSDINIEHGIISGLDGSGIDTINQNNCHSM 1063
            |  :|...:|                          |:...:|.          :..|:...|::
Zfish   184 P--NLNNFTQ--------------------------SNTKQDHS----------EAANKKYSHNV 210

  Fly  1064 NVVMNSMGPRMLNPKMCVAGGPNGPPG-FNPN----SPN---GGLRENSIGSGCGSANSSNFQGV 1120
            |...|:.....      ..|||....| |:.|    ||:   ..||.|.:..   .:.||:.:.|
Zfish   211 NCEENATQDNK------TKGGPEKLNGVFHSNNEKKSPDYRRSALRMNKVKR---RSTSSSSEPV 266

  Fly  1121 VPPG 1124
            .|.|
Zfish   267 FPCG 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lgs	NP_651922.1	BCL9	521..559	CDD:288370
pygo1	NP_001107109.1	PHD_PYGO1	267..323	CDD:277105	2/4 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23194
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100