DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lgs and Pygo1

DIOPT Version :9

Sequence 1:	NP_651922.1	Gene:	lgs / 43791	FlyBaseID:	FBgn0039907	Length:	1469	Species:	Drosophila melanogaster
Sequence 2:	NP_001178046.1	Gene:	Pygo1 / 691857	RGDID:	1594620	Length:	417	Species:	Rattus norvegicus

Alignment Length:	404	Identity:	90/404 - (22%)
Similarity:	134/404 - (33%)	Gaps:	109/404 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly  1081 VAGGPNGPPGFNPNSPNGGLRENSIGSGCGSANSSNFQGVVPPGARMMGRMPVNFGSNFNPNI-Q 1144
            |.||.:|..|.  ..||     ..:||.......::.||...|........|       |||. .
  Rat    15 VRGGDSGLDGL--GGPN-----IQLGSPDKKKRKASTQGASFPPLSEYAPPP-------NPNADH 65

  Fly  1145 VKASTP-----NTIQYMPVRAQNANNNNN----NGANNVRMPPSLEFLQRYANPQMGAVGNGSPI 1200
            :.|:.|     |||.|.|:.:.|...:..    .|.:..||||       :..|:|     .||.
  Rat    66 LVAANPFDDSYNTISYKPLPSSNPYLSPGYPGFGGYSTFRMPP-------HVPPRM-----SSPY 118

  Fly  1201 CPPSASDGTP-GMPGLMAGPGAGGMLMNSSGEQHQNKITNNPGASNGI----------------- 1247
            |.|.|....| ..|....|.|.......:.| .|.|....||..:|.:
  Rat   119 CGPYALRNQPHPFPQNPLGMGFNRPHAFNFG-PHDNSNFGNPPYNNVLTQDINMPSQHFRQGSAE 182

  Fly  1248 NFF----QNCNQMSIVDEEGGL-PGHDGSMNIGQPSMIRGMRPHAMRPNVMGARMPPVNRQIQFA 1307
            ||.    ||..|:|..|..... ||::.:.|    |.:.........||..|....|:.:| .|.
  Rat   183 NFSQIPPQNVGQVSNPDLASNFAPGNNSNFN----SPLESNHSFIPPPNSFGQAKAPLPKQ-DFT 242

  Fly  1308 QSSDGIDCVGDPSSFFTNASCNSAGPHMFGSAQQANQPKTQHIKNIPSGMCQNQSGLAVAQGQIQ 1372
            |.          ::..||.:.::..||: ......||...: :||:      |::.:.....:
  Rat   243 QG----------AAKTTNQNSSTHPPHL-NMEDPVNQSNVE-LKNV------NRNNVVQENSR-- 287

  Fly  1373 LHGQGHAQGQSLIGPTNNNLMSTAGSVSATNGVSGINFVGPSSTD------LKYAQQYHSFQQQL 1431
               .|.|:      ||||:...|........|.:.:     .:||      |..::..||....:
  Rat   288 ---SGSAE------PTNNHANGTQNKPRQPRGTADL-----CTTDKSRKFSLHPSRHGHSSSDPV 338

  Fly  1432 Y----ATNTRSQQQ 1441
            |    .||..:..|
  Rat   339 YPCGICTNEVNDDQ 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lgs	NP_651922.1	BCL9	521..559	CDD:288370
Pygo1	NP_001178046.1	PHD_PYGO1	339..395	CDD:277105	4/14 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23194
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100