DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dati and znf362a

DIOPT Version :9

Sequence 1:	NP_001245421.1	Gene:	dati / 43789	FlyBaseID:	FBgn0262636	Length:	1150	Species:	Drosophila melanogaster
Sequence 2:	NP_001071201.1	Gene:	znf362a / 777625	ZFINID:	ZDB-GENE-061103-547	Length:	448	Species:	Danio rerio

Alignment Length:	553	Identity:	142/553 - (25%)
Similarity:	214/553 - (38%)	Gaps:	179/553 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 PPNQQPISHHALHHSVPQENEQLAGVQPEGPAAGSGVVGNNSSMAISGTNSTVGSKAESSHIPQQ 146
            ||:.||.       |||.:...|.      |:||:           .|....: |..:...:|..
Zfish    42 PPHLQPT-------SVPSQQPLLV------PSAGT-----------EGGQHNI-STPKLQQMPGL 81

  Fly   147 HSEQQSYGSDSFRGTQSPQLSSHHLLFNAAAAAAAAVHLKSTAMQNNLSPIGDQVQNNLRNYGQG 211
            |:          .||..|.::.|      |..|:::|                    ..|..|..
Zfish    82 HA----------HGTSQPDIALH------ARPASSSV--------------------TGRILGDV 110

  Fly   212 SLNALCGIKPKQEMDAKTPLQPLDECPHPLVQAQAQSQYGGDYYDVADPQAREISEGRALIIGLG 276
            :||          :|.||.:             :|:..:       .|...|:|.:..:....|.
Zfish   111 NLN----------LDDKTAI-------------KARGLW-------EDWHLRQIIDQPSRANHLS 145

  Fly   277 APSTVSTDDA-----QSSAPSHQLAGTGRALQTHQCKPMSPGTVGSSNLGAGRRSAPTT---ISK 333
            ..|..|:.:|     :|..||               .|.|| |:|    |..|:..||.   ...
Zfish   146 GLSLASSRNANHNTSESVTPS---------------TPTSP-TIG----GQSRQGIPTANLLSGL 190

  Fly   334 TFSQGQQSPQHSTTPSG------GSTTPDIKYNNDK---MANEIQLQLSRSSSAAAIS--ERTLE 387
            |...|.::.::|....|      |.....||..|..   :.....:..|.:..:|.|:  |....
Zfish   191 TGGPGMEALKNSGALMGPPMKSIGRGRKKIKAENTSGPLLVVPYPILASGAEQSAVITAKEGKTY 255

  Fly   388 ECWSTLQRLFMHKSAMQQIQQQIPRVGLGTHGVTGSANLGGSITPSSDTKPHQCQQCMKSFSSNH 452
            .| ......|..||.||        :...:|               ::.|||:|..|.|:|::..
Zfish   256 RC-KVCPLTFFSKSDMQ--------IHSKSH---------------TEAKPHKCPHCTKTFANAS 296

  Fly   453 QLVQHIRVHTGEKPYKCSYCDRRFKQLSHVQQHTRLHTGERPYKCHLPDCGRAFIQLSNLQQHLR 517
            .|.||:|:|.|.|||.||||::.|:||||:|||||:|||:|||||..|.|.:||.||||||.|.|
Zfish   297 YLAQHLRIHLGVKPYHCSYCEKSFRQLSHLQQHTRIHTGDRPYKCLQPGCEKAFTQLSNLQSHQR 361

  Fly   518 NHDAQVERAKNRPFHCNICGKGFATESSLRTHTSKELQLHLGVLQQHAALIGGPNATSCPVCHKL 582
            :|:      |::|:.|:.|.:.::..:||:.|           |..||  |....|..|.:|.:.
Zfish   362 SHN------KDKPYKCSNCYRAYSDSASLQIH-----------LSAHA--IKNAKAYCCSMCGRA 407

  Fly   583 FLGTEALVDHM------KHVHKEKSPPPGGSAS 609
            :.....|:.||      :|:..::|||...|.|
Zfish   408 YTSETYLMKHMSKHTVVEHLVSQQSPPRAESPS 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dati	NP_001245421.1	COG5048	<429..>511	CDD:227381	44/81 (54%)
		C2H2 Zn finger	441..461	CDD:275368	8/19 (42%)
		zf-H2C2_2	454..478	CDD:290200	14/23 (61%)
		C2H2 Zn finger	469..489	CDD:275368	14/19 (74%)
		zf-H2C2_2	481..508	CDD:290200	18/26 (69%)
		C2H2 Zn finger	497..519	CDD:275368	13/21 (62%)
		C2H2 Zn finger	533..557	CDD:275368	5/23 (22%)
		C2H2 Zn finger	576..594	CDD:275368	5/23 (22%)
		C2H2 Zn finger	667..687	CDD:275370
		C2H2 Zn finger	702..719	CDD:275370
znf362a	NP_001071201.1	C2H2 Zn finger	257..277	CDD:275368	6/28 (21%)
		zf-H2C2_2	269..294	CDD:290200	10/47 (21%)
		C2H2 Zn finger	285..305	CDD:275368	8/19 (42%)
		zf-H2C2_2	297..322	CDD:290200	14/24 (58%)
		COG5048	309..>403	CDD:227381	51/112 (46%)
		C2H2 Zn finger	313..333	CDD:275368	14/19 (74%)
		zf-H2C2_2	325..352	CDD:290200	18/26 (69%)
		C2H2 Zn finger	341..363	CDD:275368	13/21 (62%)
		zf-H2C2_2	355..379	CDD:290200	10/29 (34%)
		C2H2 Zn finger	371..391	CDD:275368	6/30 (20%)
		C2H2 Zn finger	401..421	CDD:275368	5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	2	1.870