DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dati and CG2678

DIOPT Version :9

Sequence 1:	NP_001245421.1	Gene:	dati / 43789	FlyBaseID:	FBgn0262636	Length:	1150	Species:	Drosophila melanogaster
Sequence 2:	NP_649750.1	Gene:	CG2678 / 40937	FlyBaseID:	FBgn0014931	Length:	434	Species:	Drosophila melanogaster

Alignment Length:	434	Identity:	89/434 - (20%)
Similarity:	136/434 - (31%)	Gaps:	140/434 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   337 QGQQSPQHSTTPSGGSTTPDIKYNNDKMANEIQLQLSRSSSAAAISERTLEECWSTLQRLFMHKS 401
            |.:||.||.......|..|:         |::.|..........|:::            ...||
  Fly    77 QSEQSYQHFFRVLNQSGAPE---------NQVHLAACNGDKNQIINQK------------MQLKS 120

  Fly   402 AMQQIQQQIPRVGLGTHGVT---------GSANLGG--------------------SITPSSDTK 437
            ..||..||:.:.......::         ...|:.|                    .:.|...|:
  Fly   121 DRQQDTQQMTKTQKPDDDLSQKQTLQAKLQEGNIDGPPESFTLHPRKRTCRTEEQADMIPKEATR 185

  Fly   438 P----------HQCQQCMKSFSSNHQLVQHIRVHTGEKPYKCSYCDRRFKQLSHVQQHTRLHTGE 492
            .          :.|..|.|.|.|..||    |.|..:...:|.||.|.:.|.|::::|.|.|..:
  Fly   186 STKMICDADGYYNCPHCSKRFCSQTQL----RTHITDLCNRCPYCPRTYMQKSNLKRHLRNHLSK 246

  Fly   493 RPYKCHLPDCGRAFIQLSNLQQHLRNHDAQVERAKNRPFHCNICGKGFATESSLRTHTSKELQLH 557
            ..:||.  .|.:||::..:|::|||.||:      :.|..|:.|...|.....|..|..:
  Fly   247 PAHKCF--HCSKAFMRKDHLKRHLRTHDS------DGPLSCSQCSAVFIEHVQLEIHRRE----- 298

  Fly   558 LGVLQQHAALIGGPNATSCPVCHKLFLGTEALVDHMKHVHKEKSPPPGGSASSQFSELNQIVTGN 622
                                  ||...|:.         ..|.:..|....|.|..:|....|.|
  Fly   299 ----------------------HKQRPGSS---------KSESTKDPDSDDSDQAQDLKPKWTKN 332

  Fly   623 G-NGTGS-----SNEQIATQCTTESNSHQATVGSSLIDSFLGKRRTANH-------PCPVCGKHY 674
            . |||.|     ..:.|...|..:.:|..|.           ||....|       .|..|.:.:
  Fly   333 TFNGTCSIPPMLKPKPICDICQKKFSSVYAL-----------KRHMLTHNRQHHLKKCTYCSEEF 386

  Fly   675 VNEGSLRKHLACHAENSQLTNSLRMWPCSVCQAVFTHENGLLTH 718
            ..|..|::|...|..:        ::.|..|..||...|.|..|
  Fly   387 KTEKHLKRHERGHMGD--------LFRCEFCSLVFVDVNYLRKH 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dati	NP_001245421.1	COG5048	<429..>511	CDD:227381	25/91 (27%)
		C2H2 Zn finger	441..461	CDD:275368	8/19 (42%)
		zf-H2C2_2	454..478	CDD:290200	7/23 (30%)
		C2H2 Zn finger	469..489	CDD:275368	8/19 (42%)
		zf-H2C2_2	481..508	CDD:290200	8/26 (31%)
		C2H2 Zn finger	497..519	CDD:275368	8/21 (38%)
		C2H2 Zn finger	533..557	CDD:275368	5/23 (22%)
		C2H2 Zn finger	576..594	CDD:275368	3/17 (18%)
		C2H2 Zn finger	667..687	CDD:275370	5/19 (26%)
		C2H2 Zn finger	702..719	CDD:275370	7/17 (41%)
CG2678	NP_649750.1	zf-AD	8..85	CDD:214871	4/7 (57%)
		COG5048	220..>284	CDD:227381	23/71 (32%)
		C2H2 Zn finger	223..243	CDD:275368	8/19 (42%)
		zf-C2H2	249..271	CDD:278523	9/23 (39%)
		C2H2 Zn finger	251..271	CDD:275368	8/21 (38%)
		C2H2 Zn finger	279..299	CDD:275368	5/46 (11%)
		C2H2 Zn finger	350..370	CDD:275368	5/30 (17%)
		C2H2 Zn finger	379..399	CDD:275368	5/19 (26%)
		C2H2 Zn finger	406..427	CDD:275368	7/17 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100