DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dati and CG10654

DIOPT Version :9

Sequence 1:	NP_001245421.1	Gene:	dati / 43789	FlyBaseID:	FBgn0262636	Length:	1150	Species:	Drosophila melanogaster
Sequence 2:	NP_001261767.1	Gene:	CG10654 / 39428	FlyBaseID:	FBgn0036294	Length:	412	Species:	Drosophila melanogaster

Alignment Length:	274	Identity:	60/274 - (21%)
Similarity:	106/274 - (38%)	Gaps:	53/274 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   345 STTPSGGSTTPDIKYNND-------KMANEIQLQLSRSSSAAAISERTLEECWSTLQRLFMHKSA 402
            ||.|...|..|.|....:       ::...:.:.|||.:..|::.|.
  Fly   143 STNPEAQSHAPCIAATQEIVSFIWPQVCLPLAVILSRITLGASLEEE------------------ 189

  Fly   403 MQQIQQQIPRVGLGTHGVTGSANLGGSITPSSDTKPHQCQQCMKSFSSNHQLVQHIRVHTGEKPY 467
            :..|:.:..:..||...::.|:.|.|:..........:|:.|.:.|.....|..|::.|.|.:||
  Fly   190 VYVIEDESAKQDLGQEKLSISSKLLGARKRRGVRHTLECRICHRGFYKPSLLEAHMQQHEGLRPY 254

  Fly   468 KCSYCDRRFKQL----SHVQQ-HTRLHTGERPYKCHLPDCGRAFIQLSNLQQHLRN-----HDAQ 522
            .|.:|.:.:.:.    ||::| |.........|.|  |.|.:.:....:|:.|:|.     |:::
  Fly   255 TCVHCAKSYARANLLESHLRQMHNNADAARIIYAC--PSCNKVYTANRSLKYHMRRTHERYHESE 317

  Fly   523 VERAKNRPFHCNICGKGFATESSLRTHTSKELQLHLGVLQQHAALIGGPNATSCPVCHKLFLGTE 587
            ...|::   .|..|||.||.::.|..|.           ..|.::.|  ....|..|.:.|...|
  Fly   318 SPDARH---ICEECGKCFARKAHLTRHK-----------MVHGSVEG--RRYCCECCDRRFYTKE 366

  Fly   588 ALVDHMKHVHKEKS 601
            .:|||:...|..|:
  Fly   367 NMVDHLLRKHGNKN 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dati	NP_001245421.1	COG5048	<429..>511	CDD:227381	19/86 (22%)
		C2H2 Zn finger	441..461	CDD:275368	5/19 (26%)
		zf-H2C2_2	454..478	CDD:290200	8/23 (35%)
		C2H2 Zn finger	469..489	CDD:275368	6/24 (25%)
		zf-H2C2_2	481..508	CDD:290200	7/27 (26%)
		C2H2 Zn finger	497..519	CDD:275368	6/26 (23%)
		C2H2 Zn finger	533..557	CDD:275368	8/23 (35%)
		C2H2 Zn finger	576..594	CDD:275368	7/17 (41%)
		C2H2 Zn finger	667..687	CDD:275370
		C2H2 Zn finger	702..719	CDD:275370
CG10654	NP_001261767.1	zf-AD	39..115	CDD:285071
		C2H2 Zn finger	228..248	CDD:275368	5/19 (26%)
		C2H2 Zn finger	256..313	CDD:275368	13/58 (22%)
		C2H2 Zn finger	289..314	CDD:275368	6/26 (23%)
		zf-C2H2	323..345	CDD:278523	8/35 (23%)
		C2H2 Zn finger	325..345	CDD:275368	8/30 (27%)
		C2H2 Zn finger	355..376	CDD:275368	7/20 (35%)
		C2H2 Zn finger	385..405	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100