DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dati and az2

DIOPT Version :9

Sequence 1:	NP_001245421.1	Gene:	dati / 43789	FlyBaseID:	FBgn0262636	Length:	1150	Species:	Drosophila melanogaster
Sequence 2:	NP_610289.2	Gene:	az2 / 35682	FlyBaseID:	FBgn0025185	Length:	593	Species:	Drosophila melanogaster

Alignment Length:	328	Identity:	75/328 - (22%)
Similarity:	113/328 - (34%)	Gaps:	119/328 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   440 QCQQCMKSFSSNHQLVQH-IRVH-TGEKP-YKCSYCDRRFKQLSHVQQHT-RLHTGERPYKCHLP 500
            :|:.|..|||::|.|..| .|.| .|:.. ::|:.|:..|.:..|:|||: |:|. ::.:.|.:
  Fly   376 KCEVCEHSFSTDHALQAHQFRDHKMGDGGWFRCTLCELNFDRKCHLQQHSQRVHM-DKSFVCEI- 438

  Fly   501 DCGRAFIQLSNLQQHLRNHDAQVERAKNRPFHCNICGKGFATESSLRTHTSKELQLHLGVLQQHA 565
             |.|:|...:.|..|.|.||   |:...:||.|..|||.|..:..:.||          |...|.
  Fly   439 -CSRSFAFGNQLAIHKRTHD---EKHVAKPFVCEFCGKCFKQKIQMTTH----------VTAVHT 489

  Fly   566 ALIGGPNATSCPVCHKLFLGTEALVDHMKHVHKEKSPPPGGSASSQFSELNQIVTGNGNGTGSSN 630
            .:    .|..|.:|.|.||....|.||:|                  :.||
  Fly   490 KI----RAFKCDMCPKDFLTKRDLKDHVK------------------AHLN-------------- 518

  Fly   631 EQIATQCTTESNSHQATVGSSLIDSFLGKRRTANHPCPVCGKHYVNEGSLRKHLACHAENSQLTN 695
                                           ..:..|.||.|.:.|..:|.||...|.|
  Fly   519 -------------------------------IRDKVCEVCQKAFTNANALVKHRHIHKE------ 546

  Fly   696 SLRMWPCSVCQAVFTHENGLLTHMESMRMDPKHQFAAQYVLSRAAAEQRERESLLAVTLAASSGA 760
              :...||:|...|:....|..||                        |....:|..:|::|...
  Fly   547 --KTLQCSLCTTRFSERVSLGVHM------------------------RRTHKILKSSLSSSDAL 585

  Fly   761 STR 763
            .|:
  Fly   586 FTK 588

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dati	NP_001245421.1	COG5048	<429..>511	CDD:227381	24/74 (32%)
		C2H2 Zn finger	441..461	CDD:275368	9/20 (45%)
		zf-H2C2_2	454..478	CDD:290200	8/26 (31%)
		C2H2 Zn finger	469..489	CDD:275368	8/20 (40%)
		zf-H2C2_2	481..508	CDD:290200	10/27 (37%)
		C2H2 Zn finger	497..519	CDD:275368	7/21 (33%)
		C2H2 Zn finger	533..557	CDD:275368	7/23 (30%)
		C2H2 Zn finger	576..594	CDD:275368	8/17 (47%)
		C2H2 Zn finger	667..687	CDD:275370	8/19 (42%)
		C2H2 Zn finger	702..719	CDD:275370	5/16 (31%)
az2	NP_610289.2	MADF_DNA_bdg	157..242	CDD:287510
		GT1	276..>341	CDD:304916
		C2H2 Zn finger	377..398	CDD:275368	9/20 (45%)
		C2H2 Zn finger	408..429	CDD:275368	8/20 (40%)
		C2H2 Zn finger	436..456	CDD:275368	7/21 (33%)
		C2H2 Zn finger	467..488	CDD:275368	8/30 (27%)
		C2H2 Zn finger	496..516	CDD:275368	9/37 (24%)
		C2H2 Zn finger	524..544	CDD:275368	8/19 (42%)
		C2H2 Zn finger	551..572	CDD:275368	8/44 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100