DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dati and znf362b

DIOPT Version :9

Sequence 1:NP_001245421.1 Gene:dati / 43789 FlyBaseID:FBgn0262636 Length:1150 Species:Drosophila melanogaster
Sequence 2:NP_001083017.1 Gene:znf362b / 100038768 ZFINID:ZDB-GENE-070424-35 Length:438 Species:Danio rerio


Alignment Length:538 Identity:132/538 - (24%)
Similarity:200/538 - (37%) Gaps:145/538 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    82 PPNQQP--ISHHALHHSVPQENEQLAGVQPEGPAAGSGVVGNNSSMAISGTNSTVGSKAESSHIP 144
            ||...|  :.:..|   :.:..|||...:...|......|.:..::.::...|..|....|  ||
Zfish    14 PPPSMPGQLDNLVL---IDKIKEQLMAEKIRPPHLPPTTVPSQQTLLVASQPSDAGQHVMS--IP 73

  Fly   145 QQHSEQQSYGSDSFRGTQSPQLSSHHLLFNAAAAAAAAVHL----KSTAMQNNLSP---IGDQVQ 202
            :.   ||..|..:...:| |.::.|     |..|::....|    |||.....|..   :...|:
Zfish    74 KL---QQVPGLQAHNSSQ-PDIALH-----ARPASSTIAELSIDDKSTVKAKGLWEDWHMRQAVE 129

  Fly   203 NNLRNYGQGSLNALCGIKPKQEMDAKTPLQPLDECPHPLVQAQAQSQYGGDYYDVADPQAREISE 267
            ...|...:..|............:|.||..|...                             |:
Zfish   130 QASRTNHRSGLTLSSRTDSHNTSEAITPTTPTSS-----------------------------SQ 165

  Fly   268 GRALIIGLGAPSTVSTDDAQSSAPSHQLAGTGRALQTHQCKPMSPGTVGSSNLGAGRRSAPTTIS 332
            .|     ||..::::|....:|.|..:...:|..:.....:|.:|         .||:..     
Zfish   166 NR-----LGGAASLNTISGLASGPGMEHIKSGGLVGMLGPQPKAP---------RGRKKI----- 211

  Fly   333 KTFSQGQQSPQHSTTPSGGSTTPDIKYNNDKMANEIQLQLSRSSSAAAISERTLEECWSTLQRLF 397
                    ..:|:|.|              .:.....|..|....|..|::...........|..
Zfish   212 --------KAEHNTGP--------------LLVVPYPLLASGPDQAVTIAKEGKTYRCKVCPRTC 254

  Fly   398 MHKSAMQQIQQQIPRVGLGTHGVTGSANLGGSITPSSDTKPHQCQQCMKSFSSNHQLVQHIRVHT 462
            .:||.||        :...:|               ::.|||:|..|.|||::...|.||:|:|.
Zfish   255 FNKSEMQ--------IHSKSH---------------TEAKPHKCPHCSKSFANASYLAQHLRIHL 296

  Fly   463 GEKPYKCSYCDRRFKQLSHVQQHTRLHTGERPYKCHLPDCGRAFIQLSNLQQHLRNHDAQVERAK 527
            |.|||.||||:..|:||||:|||||:|||:|||||..|.|.:||.||||||.|.|.|:      |
Zfish   297 GIKPYHCSYCENSFRQLSHLQQHTRIHTGDRPYKCAQPGCEKAFTQLSNLQSHQRQHN------K 355

  Fly   528 NRPFHCNICGKGFATESSLRTHTSKELQLHLGVLQQHAALIGGPNATS--CPVCHKLFLGTEALV 590
            ::|:.|..|.:.:...:||:.|           |..||.    .||.|  |.:|.:.:.....|:
Zfish   356 DKPYKCPNCYRAYTDSASLQIH-----------LSAHAI----KNAKSYCCSMCGRAYTSETYLM 405

  Fly   591 DHM------KHVHKEKSP 602
            .||      :|:....||
Zfish   406 KHMSKHTVVEHLVSHHSP 423

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
datiNP_001245421.1 COG5048 <429..>511 CDD:227381 45/81 (56%)
C2H2 Zn finger 441..461 CDD:275368 9/19 (47%)
zf-H2C2_2 454..478 CDD:290200 14/23 (61%)
C2H2 Zn finger 469..489 CDD:275368 14/19 (74%)
zf-H2C2_2 481..508 CDD:290200 18/26 (69%)
C2H2 Zn finger 497..519 CDD:275368 13/21 (62%)
C2H2 Zn finger 533..557 CDD:275368 5/23 (22%)
C2H2 Zn finger 576..594 CDD:275368 5/23 (22%)
C2H2 Zn finger 667..687 CDD:275370
C2H2 Zn finger 702..719 CDD:275370
znf362bNP_001083017.1 C2H2 Zn finger 247..267 CDD:275368 5/27 (19%)
zf-H2C2_2 259..284 CDD:290200 11/47 (23%)
C2H2 Zn finger 275..295 CDD:275368 9/19 (47%)
zf-H2C2_2 287..312 CDD:290200 14/24 (58%)
C2H2 Zn finger 303..323 CDD:275368 14/19 (74%)
zf-H2C2_2 315..342 CDD:290200 18/26 (69%)
C2H2 Zn finger 331..353 CDD:275368 13/21 (62%)
zf-H2C2_2 345..369 CDD:290200 10/29 (34%)
C2H2 Zn finger 361..381 CDD:275368 6/30 (20%)
C2H2 Zn finger 395..411 CDD:275368 3/15 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
ZFIN 00.000 Not matched by this tool.
21.870

Return to query results.
Submit another query.