Sequence 1: | NP_524621.2 | Gene: | Hcf / 43788 | FlyBaseID: | FBgn0039904 | Length: | 1500 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_061867.1 | Gene: | FBXO42 / 54455 | HGNCID: | 29249 | Length: | 717 | Species: | Homo sapiens |
Alignment Length: | 937 | Identity: | 188/937 - (20%) |
---|---|---|---|
Similarity: | 311/937 - (33%) | Gaps: | 345/937 - (36%) |
- Green bases have known domain annotations that are detailed below.
Fly 18 SASDLNSEHIIQAENHSFANRISMDMDVPDGHQLDSNLTGFRWKRVLNPTGPQPRPRHGHRAINI 82
Fly 83 KELMVVFGGGNEGIVDELHVYN------TVTNQWYVPVLKGDVPNGCAAYGF---VVEGT----- 133
Fly 134 -------------------------RMFVFGGMIEYGKYS--NELYELQATKWEWRKMYPESPDS 171
Fly 172 GLSPCPRLGHSFTMVGEKIFLFGGLANESDDPKNNIPKYLNDLYILDTRGVHSHNGKW--IVPKT 234
Fly 235 YGDSPPPRESHTGISFATKSNGNLNLLIYGGMSGCR--LGDLWLLETDSMTWSKPKTSGEAPLPR 297
Fly 298 SLHSSTMIGNKMYVFGGWVPLVINDSKSTTEREWKCTNTLAVLDLETMTWENVTLDTVEENVPRA 362
Fly 363 RAGHCAVGIQSRLYVWSGRDGYRKAWNNQVCCKDLWYLEVSKPLYAVKVALVRASTHALELSWTA 427
Fly 428 TTFAAAYVLQIQKIEQPLNTSSKLLSNNIVQQGTPTSAETSGINISANRSGSALGLGVEATSTVL 492
Fly 493 KLEKESLQLSGCQPETNVQ--PSVN---DLLQSMSQPSSPA---------SRADKDPLSSGGGTT 543
Fly 544 FNLSTSVASVHPQISVISSTAAVTGNDTASPSGAINSILQKFRPVVTAVRTSTTTA--------- 599
Fly 600 VSIAT---STSDPLSVRVPS-TMSANVVLSSSSSTLRIVPSVTASHSLRIASSQASGNNCRSSSA 660
Fly 661 INILKTALPNVAVQSQPTSSTTTSIGGKQYFIQKPLTLAPNVQLQFVKTSGGMTVQTLPKVNFTA 725
Fly 726 SKG-------TPPHGISIANP---HLASGITQIQGSTVPGSQIQKPIVS---GNVLKLVS----- 772
Fly 773 --PHTMAGGKLIMKNSNI--LQM-----------GKVTPNVMG-----GKPAFVITNKQGTPLGN 817
Fly 818 QQIIIVTTGG------NVRSVPTSTVM 838 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Hcf | NP_524621.2 | Kelch_1 | 73..110 | CDD:279660 | 8/42 (19%) |
KELCH repeat | 74..115 | CDD:276965 | 11/46 (24%) | ||
KELCH repeat | 123..175 | CDD:276965 | 18/86 (21%) | ||
Kelch_3 | 132..184 | CDD:290151 | 16/83 (19%) | ||
Kelch_5 | 175..221 | CDD:290565 | 9/45 (20%) | ||
KELCH repeat | 178..239 | CDD:276965 | 11/62 (18%) | ||
Kelch_3 | 260..305 | CDD:290151 | 16/46 (35%) | ||
KELCH repeat | 297..360 | CDD:276965 | 8/62 (13%) | ||
Kelch_3 | 306..371 | CDD:290151 | 9/64 (14%) | ||
FN3 | <1307..1338 | CDD:238020 | |||
FN3 | 1344..1448 | CDD:238020 | |||
FBXO42 | NP_061867.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..34 | 6/30 (20%) | |
F-box-like | 47..>82 | CDD:315592 | 9/41 (22%) | ||
KELCH repeat | 119..168 | CDD:276965 | 10/52 (19%) | ||
Kelch_3 | 130..182 | CDD:315978 | 15/55 (27%) | ||
Kelch 1 | 132..184 | 15/55 (27%) | |||
KELCH repeat | 174..229 | CDD:276965 | 11/62 (18%) | ||
Kelch_3 | 183..240 | CDD:315978 | 14/64 (22%) | ||
Kelch 2 | 186..242 | 14/63 (22%) | |||
Guanylate_kin | 228..>360 | CDD:331880 | 44/213 (21%) | ||
Kelch_5 | 229..268 | CDD:316377 | 12/44 (27%) | ||
KELCH repeat | 232..271 | CDD:276965 | 9/44 (20%) | ||
Kelch 3 | 244..293 | 20/63 (32%) | |||
Kelch 4 | 295..342 | 14/93 (15%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 361..474 | 33/167 (20%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 570..631 | 17/69 (25%) | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R1494 |
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.940 |