Protein Alignment Hcf and Klhdc9

DIOPT Version :10

• Sequence 1: NP_524621.2
• Gene: Hcf / 43788
• FlyBaseID: FBgn0039904
• Length: 1500
• Species: Drosophila melanogaster
• Sequence 2: NP_001101820.1
• Gene: Klhdc9 / 360878
• RGDID: 1561025
• Length: 350
• Species: Rattus norvegicus
• Alignment Length: 238
• Identity: 60/238 - (25%)
• Similarity: 87/238 - (36%)
• Gaps: 80/238 - (33%)

  Fly   155 QATKWEWRKMYPESPDSGLSPCPRLGHSFTMVGEKIFLFGGLANESDDPKNNIPKYLNDLYILD- 218
            :.:.|.||   |.:.|:.|:   |..||.|.:..:.:|.|||.    :....:|.  ||..|.|
  Rat    11 RGSTWTWR---PVARDALLA---RAFHSCTELEGRFYLVGGLL----EGGARVPS--NDTVIFDP 63

  Fly   219 ---------TRG--VHSHN------GKWIVPKTYGDSPPPRESHTGISFATKSNGNLNLLIYGGM 266
                     .||  :.||:      |:|                              |.:.||.
  Rat    64 ARGQAVRLLARGGPLRSHHDAALVGGRW------------------------------LCVVGGW 98

  Fly   267 SGC-RLGDLWLLETDSMTW----SKPKTSGEAPLPRSLHSSTMIGNKMYVFGGWVPLVINDSKST 326
            .|. ||..:..|:|.|..|    :||.....|.|  |.|:.|.|.::.:...|      .:..:.
  Rat    99 DGSRRLSTVAALDTSSGVWEVWTAKPANCPPAGL--SSHTCTRISDREFRVSG------REGGTR 155

  Fly   327 TEREWKCTNTLAVLDLETMTWENVTLDTVEENVPRA-RAGHCA 368
            |:|.:....||. ||..|.|:     ...||....| |:||||
  Rat   156 TQRRYGSIYTLK-LDHSTRTY-----CYKEEGCHTASRSGHCA 192

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hcf	NP_524621.2	PLN02193	<59..363	CDD:177844	55/231 (24%)
		KELCH repeat	74..115	CDD:276965
		KELCH repeat	123..175	CDD:276965	6/19 (32%)
		KELCH repeat	178..239	CDD:276965	19/78 (24%)
		KELCH repeat	297..360	CDD:276965	15/62 (24%)
		FN3	<1307..>1381	CDD:442628
		FN3	<1307..1338	CDD:238020
		FN3	1344..1448	CDD:238020
Klhdc9	NP_001101820.1	NanM	16..350	CDD:442289	59/233 (25%)
		KELCH repeat	28..76	CDD:276965	14/53 (26%)
		KELCH repeat	79..119	CDD:276965	14/69 (20%)
		KELCH repeat	187..245	CDD:276965	5/6 (83%)
		KELCH repeat	259..311	CDD:276965