Protein Alignment PMCA and AT3G63380

DIOPT Version :10

• Sequence 1: NP_001014689.3
• Gene: PMCA / 43787
• FlyBaseID: FBgn0259214
• Length: 1255
• Species: Drosophila melanogaster
• Sequence 2: NP_191897.1
• Gene: AT3G63380 / 825513
• AraportID: AT3G63380
• Length: 1033
• Species: Arabidopsis thaliana
• Alignment Length: 1117
• Identity: 399/1117 - (35%)
• Similarity: 615/1117 - (55%)
• Gaps: 183/1117 - (16%)

  Fly     2 ATIDGRPAQY--GISLKQLRELMEHRGREGVMKIAENGGIHELCKKLYTSPNEGLSGSKADEEHR 64
            |.|:..|..|  .|..:||.|:|:.:...|:..:   ||:..:...|.|:|.:|:.|::.:...|
plant    75 AKINSMPLSYVPAIDQEQLVEIMKGKDLPGIQAL---GGVEGVAASLRTNPTKGIHGNEQEVSRR 136

  Fly    65 RETFGSNVIPPKPPKTFLTLVWEALQDVTLIILEVAALVSLGLSFYKPADEDAPVLQEEEEHHGW 129
            |:.||||.....|||..|..|:||.:|:|::||.|.|:.|||..           ::|.....||
plant   137 RDLFGSNTYHKPPPKGLLFFVYEAFKDLTILILLVCAIFSLGFG-----------IKEHGIKEGW 190

  Fly   130 IEGLAILISVIVVVIVTAFNDYSKERQFRGLQNRIEGEHKFSVIRGGEVCQISVGDILVGDIAQV 194
            .||.:|.::|.:|::|:|.:::.:||||..| ::|....|..|:|......||:.|::|||:..:
plant   191 YEGGSIFVAVFLVIVVSALSNFRQERQFDKL-SKISNNIKVEVLRDSRRQHISIFDVVVGDVVFL 254

  Fly   195 KYGDLLPADGCLIQSNDLKVDESSLTGESDHVKKGPDVDPMVLSGTHVMEGSGKMVVTAVGVNSQ 259
            |.||.:||||..::.:.|:|||||:||||||::.....:|.:.|||.:::|..:|:|.:||:::.
plant   255 KIGDQIPADGLFLEGHSLQVDESSMTGESDHLEVDHKDNPFLFSGTKIVDGFAQMLVVSVGMSTT 319

  Fly   260 AGIIFTLLGAAVDEQEAEIKKMKKEAKRANKQKNLTGENDGRSQIKGSQAPSQRETVTSEITKSE 324
            .|                                                    :|::|
plant   320 WG----------------------------------------------------QTMSS------ 326

  Fly   325 SEGNHLPQSSSSGAAETGHKKEKSVLQAKLTKLAIQIGYAGSTIAVLTVIILIIQFCIKTFVIDE 389
                 :.|.||          |::.||.:|..|...||..|.|:|.|.:::|::::....   .|
plant   327 -----INQDSS----------ERTPLQVRLDTLTSTIGKIGLTVAALVLVVLLVRYFTGN---TE 373

  Fly   390 KPWKNTY----------ANNLVKHLIIGVTVLVVAVPEGLPLAVTLSLAYSVKKMMKDNNLVRHL 444
            |..|..|          .|::|:.:...||::|||:||||||||||:||||:|:||.|..:||.|
plant   374 KEGKREYNGSKTPVDTVVNSVVRIVAAAVTIVVVAIPEGLPLAVTLTLAYSMKRMMSDQAMVRKL 438

  Fly   445 DACETMGNATAICSDKTGTLTTNRMTVV-----QSYICEKLCKVL-PTLSDIPQHVGNLITMGIS 503
            .||||||:||.||:|||||||.|.|.|.     |..|.|...|:: |.:.|       |:..|..
plant   439 SACETMGSATVICTDKTGTLTLNEMKVTKFWLGQESIHEDSTKMISPDVLD-------LLYQGTG 496

  Fly   504 VNSAYTSNIMAGHNPGDLPIQVGNKTECALLGF-VQGLGVKYQSIRDEITEDKFTRVYTFNSVRK 567
            :|   |:..:...:.|..|...|:.||.|||.: |..||:..:|::.   :.:..||.||:|.:|
plant   497 LN---TTGSVCVSDSGSTPEFSGSPTEKALLSWTVLNLGMDMESVKQ---KHEVLRVETFSSAKK 555

  Fly   568 SMGTVIPRPNGG-YRLYTKGASEIIMKKCAFIYGHEGTLEKFTRDMQERLIREVIEPMACDGLRT 631
            ..|.::.|.:.. ..::.|||:|:::..|:..|...|:::......:.| |:.:|:.||...||.
plant   556 RSGVLVRRKSDNTVHVHWKGAAEMVLAMCSHYYTSTGSVDLMDSTAKSR-IQAIIQGMAASSLRC 619

  Fly   632 ISVAYRDFVPGKAAINEVHIDGEPNWDDEENIMTNLTCLCVVGIEDPVRPEVPDAIRKCQRAGIT 696
            |:.|:      |.|.|:..::.:           .||.:.:||::||.||.|..|:..|:.||:|
plant   620 IAFAH------KIASNDSVLEED-----------GLTLMGIVGLKDPCRPGVSKAVETCKLAGVT 667

  Fly   697 VRMVTGDNINTARSIASKCGILRPND---DFLILEGKEFNRRIRDSNGDIQQHLIDKVWPKLRVL 758
            ::|:||||:.||::||.:||||..||   :..::||.:|    |:...:.:...:||:    ||:
plant   668 IKMITGDNVFTAKAIAFECGILDHNDKDEEDAVVEGVQF----RNYTDEERMQKVDKI----RVM 724

  Fly   759 ARSSPTDKYTLVKGIIDSTVSENREVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIIL 823
            |||||:||..:||     .:.....|||||||||||.||||:||:|.:|||.||:||||:|||::
plant   725 ARSSPSDKLLMVK-----CLRLKGHVVAVTGDGTNDAPALKEADIGLSMGIQGTEVAKESSDIVI 784

  Fly   824 TDDNFSSIVKAVMWGRNVYDSIAKFLQFQLTVNVVAVIVAFIGACAVQDSPLKAVQMLWVNLIMD 888
            .||||:|:...:.|||.||::|.||:||||||||.|:::.||.|.:..:.||.|||:||||||||
plant   785 LDDNFASVATVLKWGRCVYNNIQKFIQFQLTVNVAALVINFIAAISAGEVPLTAVQLLWVNLIMD 849

  Fly   889 TLASLALATEFPTPDLLLRKPYGRTKPLISRTMMKNILGQALYQLIIIFGLLFVGDVILDIESGR 953
            ||.:||||||.||.:||.|||.|||:.||:..|.:|:|.|:|||:.::..|.|.|..|..:.
plant   850 TLGALALATERPTNELLKRKPVGRTEALITNVMWRNLLVQSLYQIAVLLILQFKGMSIFSVR--- 911

  Fly   954 GQELNAGPTQHFTIIFNTFVMMTLFNEINARKIHGQRNVIEGLLTNPIFYTIWIFTMISQVLIIQ 1018
             :|:..      |:||||||:..:|||.|||::. ::||.:||..|.:|..|...|::.||::::
plant   912 -KEVKD------TLIFNTFVLCQVFNEFNAREME-KKNVFKGLHRNRLFIGIIAITIVLQVIMVE 968

  Fly  1019 YGKMAFSTKALTLDQWLWCIFFGIGTLVW--GQLITSVPTRKLPKILSWGRGHPEEYTDGMNLGE 1081
            :.|....|  :.|:.|.|.....:.:|.|  |.....:|..:.| .||:.: :|.....|
plant   969 FLKKFADT--VRLNGWQWGTCIALASLSWPIGFFTKFIPVSETP-FLSYFK-NPRSLFKG----- 1024

  Fly  1082 ERFDSIDSDKKP 1093
            .|..|:   |||
plant  1025 SRSPSL---KKP 1033

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PMCA	NP_001014689.3	P-type_ATPase_Ca_PMCA-like	62..921	CDD:319776	328/879 (37%)
		Cation_ATPase_C	873..1051	CDD:376368	76/179 (42%)
		ATP_Ca_trans_C	1096..1141	CDD:463575
AT3G63380	NP_191897.1	P-type_ATPase_Ca_PMCA-like	133..882	CDD:319776	328/880 (37%)
		Cation_ATPase_C	833..1004	CDD:376368	76/183 (42%)