Protein Alignment PMCA and ACA7

DIOPT Version :10

• Sequence 1: NP_001014689.3
• Gene: PMCA / 43787
• FlyBaseID: FBgn0259214
• Length: 1255
• Species: Drosophila melanogaster
• Sequence 2: NP_179879.1
• Gene: ACA7 / 816826
• AraportID: AT2G22950
• Length: 1015
• Species: Arabidopsis thaliana
• Alignment Length: 1055
• Identity: 424/1055 - (40%)
• Similarity: 579/1055 - (54%)
• Gaps: 164/1055 - (15%)

  Fly     7 RPAQYGISLKQLRELMEHRGREGVMKIAENGGIHELCKKLYTSPNEGLSGSKADE-EHRRETFGS 70
            :.|.:.|...:|..::|  |.: |.|:..:||:..|..||...||.|||..:.:: ..|:|.||.
plant    90 KAAGFDICADELGSIVE--GHD-VKKLKFHGGVDGLSGKLKACPNAGLSTGEPEQLSKRQELFGI 151

  Fly    71 NVIPPKPPKTFLTLVWEALQDVTLIILEVAALVSLGLSFYKPADEDAPVLQEEEEHHGWIEGLAI 135
            |.......::|...|||||||:||:||.|.|.|||.:..   |.|..|        .|..:||.|
plant   152 NKFAESELRSFWVFVWEALQDMTLMILGVCAFVSLIVGI---ATEGWP--------QGSHDGLGI 205

  Fly   136 LISVIVVVIVTAFNDYSKERQFRGLQNRIEGEHK---FSVIRGGEVCQISVGDILVGDIAQVKYG 197
            :.|:::||.|||.:||.:..|||.|    :.|.|   ..|.|.|...::|:.|:|.||:..:..|
plant   206 VASILLVVFVTATSDYRQSLQFRDL----DKEKKKITVQVTRNGFRQKMSIYDLLPGDVVHLAIG 266

  Fly   198 DLLPADGCLIQSNDLKVDESSLTGESDHVKKGPDVDPMVLSGTHVMEGSGKMVVTAVGVNSQAGI 262
            |.:||||..:....:.:|||||||||:.|..... :|.:||||.|.:||.||:||.||:.:|.|.
plant   267 DQVPADGLFLSGFSVVIDESSLTGESEPVMVTAQ-NPFLLSGTKVQDGSCKMLVTTVGMRTQWGK 330

  Fly   263 IFTLLGAAVDEQEAEIKKMKKEAKRANKQKNLTGENDGRSQIKGSQAPSQRETVTSEITKSESEG 327
            :...|                                                         |||
plant   331 LMATL---------------------------------------------------------SEG 338

  Fly   328 NHLPQSSSSGAAETGHKKEKSVLQAKLTKLAIQIGYAGSTIAVLTVIILII-QFCIKTFVIDEKP 391
            .                .:::.||.||..:|..||..|.:.|::|..:|:. .|..|..:.....
plant   339 G----------------DDETPLQVKLNGVATIIGKIGLSFAIVTFAVLVQGMFMRKLSLGPHWW 387

  Fly   392 WKNTYANNLVKHLIIGVTVLVVAVPEGLPLAVTLSLAYSVKKMMKDNNLVRHLDACETMGNATAI 456
            |....|..|:::..|.||::|||||||||||||||||:::||||.|..|||||.||||||:||.|
plant   388 WSGDDALELLEYFAIAVTIVVVAVPEGLPLAVTLSLAFAMKKMMNDKALVRHLAACETMGSATTI 452

  Fly   457 CSDKTGTLTTNRMTVVQSYIC----EKLCKVLPTLSDIPQHVGNLITMGISVNSAYTSNIMAGHN 517
            |||||||||||.||||:|.||    :...|.....||||:....|:...|..|   |...:..:.
plant   453 CSDKTGTLTTNHMTVVKSCICMNVQDVASKSSSLQSDIPEAALKLLLQLIFNN---TGGEVVVNE 514

  Fly   518 PGDLPIQVGNKTECALLGFVQGLGVKYQSIRDEITEDKFTRVYTFNSVRKSMGTVIPRPNGG-YR 581
            .|...| :|..||.|:|.....||.|:|   :|...:|..:|..|||.:|.||.||..|.|| .|
plant   515 RGKTEI-LGTPTETAILELGLSLGGKFQ---EERQSNKVIKVEPFNSTKKRMGVVIELPEGGRIR 575

  Fly   582 LYTKGASEIIMKKCAFIYGHEGTLEKFTRDMQERLIREVIEPMACDGLRTISVAYRDFVPGKAAI 646
            .:|||||||::..|..:....|.:.... |...:.:...|:..|.:.|||:.:||.|...|.:|
plant   576 AHTKGASEIVLAACDKVINSSGEVVPLD-DESIKFLNVTIDEFANEALRTLCLAYMDIESGFSA- 638

  Fly   647 NEVHIDGEPNWDDEENIMTNLTCLCVVGIEDPVRPEVPDAIRKCQRAGITVRMVTGDNINTARSI 711
                        ||.......||:.:|||:|||||.|.:::..|:||||.||||||||||||::|
plant   639 ------------DEGIPEKGFTCIGIVGIKDPVRPGVRESVELCRRAGIMVRMVTGDNINTAKAI 691

  Fly   712 ASKCGILRPNDDFLILEGKEFNRRIRDSNGDIQQHLIDKVWPKLRVLARSSPTDKYTLVKGIIDS 776
            |.:||||  .||.:.:||..|    |:.|   |:.:::.: ||::|:|||||.||:||||.:  .
plant   692 ARECGIL--TDDGIAIEGPVF----REKN---QEEMLELI-PKIQVMARSSPMDKHTLVKQL--R 744

  Fly   777 TVSENREVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNV 841
            |..:  ||||||||||||.|||.:||:|.|||||||:||||.:|:|:.|||||:||....|||:|
plant   745 TTFD--EVVAVTGDGTNDAPALHEADIGLAMGIAGTEVAKEIADVIILDDNFSTIVTVAKWGRSV 807

  Fly   842 YDSIAKFLQFQLTVNVVAVIVAFIGACAVQDSPLKAVQMLWVNLIMDTLASLALATEFPTPDLLL 906
            |.:|.||:||||||||||:||.|..||....:||.|||:||||:|||||.:||||||.|..:|:.
plant   808 YINIQKFVQFQLTVNVVALIVNFSSACLTGSAPLTAVQLLWVNMIMDTLGALALATEPPNNELMK 872

  Fly   907 RKPYGRTKPLISRTMMKNILGQALYQLIII----------FGLLFVGDVILDIESGRGQELNAGP 961
            |.|.||....|:..|.:||||||:||.|||          |||:.....::         ||
plant   873 RMPVGRRGNFITNAMWRNILGQAVYQFIIIWILQAKGKSMFGLVGSDSTLV---------LN--- 925

  Fly   962 TQHFTIIFNTFVMMTLFNEINARKIHGQRNVIEGLLTNPIFYTIWIFTMISQVLIIQYGKMAFST 1026
                |:|||.||...:|||:::|::. :.:|.:|:|.|.:|..:...|:..|::||::.....||
plant   926 ----TLIFNCFVFCQVFNEVSSREME-EIDVFKGILDNYVFVVVIGATVFFQIIIIEFLGTFAST 985

  Fly  1027 KALTLDQWLWCIFFG 1041
            ..||:.||.:.||.|
plant   986 TPLTIVQWFFSIFVG 1000

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PMCA	NP_001014689.3	P-type_ATPase_Ca_PMCA-like	62..921	CDD:319776	362/867 (42%)
		Cation_ATPase_C	873..1051	CDD:376368	72/179 (40%)
		ATP_Ca_trans_C	1096..1141	CDD:463575
ACA7	NP_179879.1	CaATP_NAI	5..49	CDD:432606
		ATPase-IIB_Ca	99..1015	CDD:273668	422/1046 (40%)