Protein Alignment PMCA and atp2b4

DIOPT Version :10

• Sequence 1: NP_001014689.3
• Gene: PMCA / 43787
• FlyBaseID: FBgn0259214
• Length: 1255
• Species: Drosophila melanogaster
• Sequence 2: NP_001070935.1
• Gene: atp2b4 / 768304
• ZFINID: ZDB-GENE-061027-60
• Length: 316
• Species: Danio rerio
• Alignment Length: 306
• Identity: 192/306 - (62%)
• Similarity: 225/306 - (73%)
• Gaps: 25/306 - (8%)

  Fly     1 MATIDGRPAQYGISLKQLRELMEHRGREGVMKIAE-NGGIHELCKKLYTSPNEGLSGSKADEEHR 64
            :|.:| ....:|.::.|||||||.|..|.|.|||| .|.:..:|::|.|||.|||||:.||.|.|
Zfish    14 VAEVD-HEGDFGCTMMQLRELMELRSGEAVSKIAECYGDVQGICRRLKTSPIEGLSGNPADIEKR 77

  Fly    65 RETFGSNVIPPKPPKTFLTLVWEALQDVTLIILEVAALVSLGLSFYKPADED-------APVLQE 122
            ..:||.|.||||.|||||.||||||||||||||||||::||.||||.|.:.|       ..|..|
Zfish    78 HTSFGKNFIPPKKPKTFLQLVWEALQDVTLIILEVAAIISLALSFYHPPEGDNAACGEVGGVEDE 142

  Fly   123 EEEHHGWIEGLAILISVIVVVIVTAFNDYSKERQFRGLQNRIEGEHKFSVIRGGEVCQISVGDIL 187
            .|...|||||.|||.|||:||:||||||:|||:||||||:|||.|.||:|||.|:|.||.|.:|:
Zfish   143 GESQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRKGQVIQIPVAEIV 207

  Fly   188 VGDIAQVKYGDLLPADGCLIQSNDLKVDESSLTGESDHVKKGPDVDPMVLSGTHVMEGSGKMVVT 252
            ||||||:||||||||||.|||.||||:||||||||||.|:|..:.|||:|||||||||||:|||:
Zfish   208 VGDIAQIKYGDLLPADGILIQGNDLKIDESSLTGESDQVRKSLEKDPMLLSGTHVMEGSGRMVVS 272

  Fly   253 AVGVNSQAGIIFTLLGAAVDEQEAEIKKMKKEAKRANKQKNLTGEN 298
            |||:|||.|||||||||..||:    ||:||            |||
Zfish   273 AVGLNSQTGIIFTLLGAGEDEE----KKVKK------------GEN 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PMCA	NP_001014689.3	P-type_ATPase_Ca_PMCA-like	62..921	CDD:319776	162/244 (66%)
		Cation_ATPase_C	873..1051	CDD:376368
		ATP_Ca_trans_C	1096..1141	CDD:463575
atp2b4	NP_001070935.1	Haloacid Dehalogenase-like Hydrolases	74..>294	CDD:473868	154/219 (70%)