DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Rad23 and Ubl7

DIOPT Version :9

Sequence 1:NP_001259052.1 Gene:Rad23 / 43785 FlyBaseID:FBgn0026777 Length:414 Species:Drosophila melanogaster
Sequence 2:NP_001116345.1 Gene:Ubl7 / 69459 MGIID:1916709 Length:380 Species:Mus musculus


Alignment Length:378 Identity:79/378 - (20%)
Similarity:128/378 - (33%) Gaps:149/378 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 FTIEFAPEKTVLELKKKIFEERGPEYVAEKQKLIYAGVILTDDRTVGSYNV-------------- 63
            ::|.|..:....:|::.:.:   ||.:    .|||.|..|.||:|:..|.:              
Mouse    38 YSISFLKQLIAGKLQESVPD---PELI----DLIYCGRKLKDDQTLDFYGIQPGSTVHVLRKSWP 95

  Fly    64 --DEK-----------KFIVVMLTRDSSSSNRNQLSVKESNKLTSTDDSKQSMPCEEANHTNSPS 115
              |:|           :|.|:.....||||.|..:....||        |:|:            
Mouse    96 EPDQKPEPVDKVAALREFRVLHTALHSSSSYREAVFKMLSN--------KESL------------ 140

  Fly   116 STNTEDSVLSRETRPLSSDEL-IGELAQASLQS-RAESNLLMGDEYNQT--------------VL 164
                 |.::. .|..||||.: :|.|....|.| .|:.|:|      .|              ||
Mouse   141 -----DQIIV-ATPGLSSDPIALGVLQDKDLFSVFADPNML------DTLVPAHPALVNAIILVL 193

  Fly   165 SMVEMGYP---REQVERAM-AASYNNPERAVEYLINGIPAEEGTFY---NRLNESTNPSLIP--- 219
            ..|....|   .:...|:| ::||.:....  :|.:|:..:|..|:   .....|:.||..|   
Mouse   194 HSVAGSTPMPGADSSSRSMPSSSYRDMPGG--FLFDGLSDDEDDFHPSTRSTPSSSTPSSRPASL 256

  Fly   220 -----SGPQP----------ASATSAERST----------------------------------- 234
                 :||:|          |.|::.|.|:                                   
Mouse   257 GYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGTSPMSSGVQSGTPITNDLFSQA 321

  Fly   235 -----ESNSDPFEFLRSQPQFLQMRSLIYQNPHLLHAVLQQIGQTNPALLQLI 282
                 :::..|...::.|||..|:|.:..|:..|....||..|....|.|:||
Mouse   322 LQHALQASGQPSLQIQWQPQLQQLRDMGIQDDELSLRALQATGGDIQAALELI 374

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rad23NP_001259052.1 rad23 1..413 CDD:273167 79/378 (21%)
RAD23_N 1..76 CDD:176400 18/89 (20%)
UBA1_Rhp23p_like 153..199 CDD:270561 12/63 (19%)
XPC-binding 242..296 CDD:286376 14/41 (34%)
UBA2_HR23A 371..411 CDD:270610
Ubl7NP_001116345.1 Ubl_UBL7 7..98 CDD:340513 14/66 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 200..313 20/114 (18%)
UBA_UBL7 <346..375 CDD:270511 10/29 (34%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5272
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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