DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rad23 and ubl7a

DIOPT Version :9

Sequence 1:	NP_001259052.1	Gene:	Rad23 / 43785	FlyBaseID:	FBgn0026777	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_001017765.1	Gene:	ubl7a / 550462	ZFINID:	ZDB-GENE-050417-285	Length:	379	Species:	Danio rerio

Alignment Length:	406	Identity:	81/406 - (19%)
Similarity:	145/406 - (35%)	Gaps:	132/406 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 KKIFEERGPEYVAEKQ--KLIYAGVILTDDRTVGSYNVDEKKFIVVMLTRDSSSSNRNQLSVKES 90
            |::...:.|:.:.:.:  :|:|.|..|.||.|:.||.:.....:.::    ..|....::..:..
Zfish    44 KQLVSAQIPDAIPDPELIELVYCGRKLKDDLTLESYGIQSGSTVHIL----RKSWPEPEIHPEPV 104

  Fly    91 NKLTSTDDSKQSMPCEEANHTNSPSSTNTEDSVLSRETRPLSSDELI--------GELAQASLQS 147
            :|:.:   :::....:.|.||    ||...:||........|.|::|        ..:|...||.
Zfish   105 DKVAA---AREFRVLQAALHT----STAYRESVFKMLNNKESLDQIIVATPGLSSDPVALGVLQD 162

  Fly   148 R------AESNLL--MGDEYNQ------TVLSMVEMGYPREQ----VERAMAASYNNPERAVEYL 194
            :      |:.|:|  :.:.:..      .||..|....|.:|    .....:.||::....  :|
Zfish   163 KDLFLQFADPNMLDTLANSHPALVNAIILVLHSVAGSVPPQQSTSSSRNVSSGSYSDMPGG--FL 225

  Fly   195 INGIPAEEGTFY--NRLNESTNPSLIPSGPQPAS-----ATSAERSTESNSDPFEFLRSQPQFLQ 252
            ..|:..:|..|.  ||...||..|.: :|.:|||     |......|:|.......|.|.|:
Zfish   226 FEGMSDDEEDFQSGNRGGPSTLASGL-AGMRPASLGYNGAVGPRPITQSELATALALASTPE--- 286

  Fly   253 MRSLIYQNPHLLHAVLQQIGQTNPALLQLISENQDAFLNMLNQPIDRESESGAT-VP---PVSNA 313
                       ..||....|...|:                         ||.: :|   |::|
Zfish   287 -----------SSAVTPTTGNQGPS-------------------------SGVSPIPAGTPITN- 314

  Fly   314 RIPSTLDNVDLFSPDLEVATSAQRSAAGTSAAHQSGSAADNEDLEQPLGVSTI-RLNRQDKDAIE 377
                     |||                            |:.|:|.|.||:: .|:.|.:..::
Zfish   315 ---------DLF----------------------------NQALQQALQVSSMSSLHNQWQSQLQ 342

  Fly   378 RLKALGF-PEALVLQA 392
            :|:.:|. .|.|:|:|
Zfish   343 QLRDMGIRDEELILRA 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rad23	NP_001259052.1	rad23	1..413	CDD:273167	81/406 (20%)
		RAD23_N	1..76	CDD:176400	11/49 (22%)
		UBA1_Rhp23p_like	153..199	CDD:270561	10/57 (18%)
		XPC-binding	242..296	CDD:286376	7/53 (13%)
		UBA2_HR23A	371..411	CDD:270610	7/23 (30%)
ubl7a	NP_001017765.1	UBQ	19..92	CDD:294102	11/51 (22%)
		UBQ	<40..88	CDD:214563	11/43 (26%)
		UBA_UBL7	337..374	CDD:270511	6/22 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900