DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rad23 and RGD1562433

DIOPT Version :9

Sequence 1:NP_001259052.1 Gene:Rad23 / 43785 FlyBaseID:FBgn0026777 Length:414 Species:Drosophila melanogaster
Sequence 2:NP_001071146.1 Gene:RGD1562433 / 499222 RGDID:1562433 Length:510 Species:Rattus norvegicus


Alignment Length:524 Identity:107/524 - (20%)
Similarity:181/524 - (34%) Gaps:152/524 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 ITIKNLQ--QQTFTIEFAPEKTVLELKKKIFEERGPEYV---AEKQKLIYAGVILTDDRTVGSYN 62
            :::|..|  |:.|   .|....|...||:|     .:|:   .::..|||.|.||.|...:....
  Rat    26 VSVKTPQDCQEFF---LAENSNVHRFKKQI-----SKYLHCDTDRLVLIYTGKILQDQDILSQRG 82

  Fly    63 V-DEKKFIVVMLTRDSSS-------------SNRNQLSVKESNKLTSTDDSK-------QSMPC- 105
            : |......|:.:|...|             ::|::.|||......|:.|..       |.:|. 
  Rat    83 ILDGSTVHAVVRSRLKGSACTGTLAGPTGHCTHRSEPSVKLGRLARSSPDLADFFSQLVQLLPAA 147

  Fly   106 -------------------EEANHTNSPSSTNT---EDSVLS-RET--RPLSSDELIGE------ 139
                               ::||..:.|.|:.|   .|..|. .||  :|:...|::.|      
  Rat   148 PESVVQFLEDPLIQGLANEKQANGVHIPESSKTVQKRDPALKFPETFQKPVQQQEVLQEHKQRLE 212

  Fly   140 ------------------LAQASLQSRAE----------SNLLMGDEYNQTVLSMVEMGYPREQV 176
                              :.||.|.:.|.          |:|..|:..|           ....:
  Rat   213 ALKAVPGGDNAMHPSCSDIQQAMLSTLASLVASKGHISGSDLCRGEANN-----------AHSSL 266

  Fly   177 ERAMAASYNNPER--AVEYLINGIPAEEGTFYNRLNESTNPSLIPSGPQPASATSAERSTESNSD 239
            :.....:.:.|.|  |.|....|:...:|...::........::...|      |:|..::.:..
  Rat   267 DTTTIPATSAPVRTLAQEVSTGGVTQVKGLVSSQAGSGCRQGMLDLHP------SSETPSQESQQ 325

  Fly   240 PFE------FLRSQPQFLQMR-SLIYQNPHLLH------AVLQQIG----QTNPALLQLISENQD 287
            |.|      .||..|..|:.. :::.|||.|.|      .:|..|.    .|||..||.:.:.::
  Rat   326 PVEKVPLTNQLRLSPSVLRRALTVLQQNPSLAHQLATGSPLLHHIPLLPILTNPRALQALLQIEE 390

  Fly   288 AFLNMLNQ-----PIDRESES--GATVPPVSNARIPSTLDNVDLFSPDLEVATSAQRSAAGTSAA 345
            ..:.:..:     |:.|||..  ||.....:..|..:..::            ::|.|.|.....
  Rat   391 GLMILSREVPELGPLFRESAKPRGARGAQETRGRRQAHRED------------TSQHSLAFLQLF 443

  Fly   346 HQSGSAADNEDLEQPLGVSTIRLNRQDKDAIERLKALGFP-EALVLQAYFACEKNEEQAANFLLS 409
            |...||. ::..:..|..|....:|..:: :|.||||||. ....|||..|.:.:...|...||.
  Rat   444 HSLASAC-SQSTQTALPASPFTEDRYQQE-LEELKALGFANHDANLQALVATDGDIHAAIEKLLG 506

  Fly   410 SSFD 413
            :..|
  Rat   507 APQD 510

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rad23NP_001259052.1 rad23 1..413 CDD:273167 106/522 (20%)
RAD23_N 1..76 CDD:176400 19/78 (24%)
UBA1_Rhp23p_like 153..199 CDD:270561 8/47 (17%)
XPC-binding 242..296 CDD:286376 17/75 (23%)
UBA2_HR23A 371..411 CDD:270610 14/40 (35%)
RGD1562433NP_001071146.1 UBQ 24..94 CDD:214563 19/75 (25%)
UBQ 24..94 CDD:294102 19/75 (25%)
UBA_PLICs 467..506 CDD:270582 14/39 (36%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5272
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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