DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rad23 and ubl7b

DIOPT Version :9

Sequence 1:	NP_001259052.1	Gene:	Rad23 / 43785	FlyBaseID:	FBgn0026777	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	XP_005173742.1	Gene:	ubl7b / 393331	ZFINID:	ZDB-GENE-040426-1334	Length:	371	Species:	Danio rerio

Alignment Length:	358	Identity:	70/358 - (19%)
Similarity:	124/358 - (34%)	Gaps:	132/358 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 IYAGVILTDDRTVGSYNVDEKKFIVVMLTRDSSSSNRNQLSVKESNKLTSTDDSKQSMPCEEANH 110
            ::.|.:|.||.|:.||.:.....:.::                           |::.|..|.
Zfish    61 VHCGCVLKDDLTLDSYGIKSGSTLHII---------------------------KKTWPEPEI-- 96

  Fly   111 TNSPSSTNTEDSVLSRETRPLSSDELIGELAQASLQSRAESNLLMGDEYNQTVLSMVEMGYPREQ 175
              .|...|.  |..:||.|.|          ||::.|.|        .|.:.|..|:.   .:|.
Zfish    97 --QPEPVNR--SAAAREFRML----------QAAMLSNA--------TYREAVFKMLA---NKES 136

  Fly   176 VERAMAASYNNPERAVEYLINGIPAEEGTFYNRLNESTNPSLIPSGPQPASATSAERSTESNSDP 240
            :::.:.||   |..:.:.:...:..::..|.    :.|:|:|:.:
Zfish   137 LDQIIVAS---PGLSSDPVALAVLQDKDLFV----QFTDPNLLDT-------------------- 174

  Fly   241 FEFLRSQPQFLQMRSLIYQNPHLLHAVLQQIGQTNPA-----------------LLQLISENQDA 288
              .:||.|..:....||      ||:|....||::..                 |...:|:::|.
Zfish   175 --LIRSHPSLVNAIILI------LHSVTSSSGQSSSGSSRSTAASSYSQMPGGFLFDGMSDDEDD 231

  Fly   289 FLNMLNQPIDRESESGATVPPVSNARIPSTLDNVDLFSP------DLEVATS-AQRSAAGTSAAH 346
            |        ...|..|::.|..::...|.||.:.....|      :|..|.: |....||.:|..
Zfish   232 F--------QSASRGGSSWPLRASGSRPGTLAHSGAMGPRPITQSELTHALALASTPEAGGTAPA 288

  Fly   347 QSGSAAD--------NEDLEQPL---GVSTIRL 368
            |.||||.        :..|:|.|   |||::::
Zfish   289 QDGSAAGAPVSSGLFSHALQQALQASGVSSLQV 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rad23	NP_001259052.1	rad23	1..413	CDD:273167	70/358 (20%)
		RAD23_N	1..76	CDD:176400	7/29 (24%)
		UBA1_Rhp23p_like	153..199	CDD:270561	7/45 (16%)
		XPC-binding	242..296	CDD:286376	14/70 (20%)
		UBA2_HR23A	371..411	CDD:270610
ubl7b	XP_005173742.1	BMSC_UbP_N	15..89	CDD:176410	7/54 (13%)
ubl7b	XP_005173742.1	Herpes_capsid	<232..300	CDD:283714	19/75 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900