DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rad23 and Oas1i

DIOPT Version :9

Sequence 1:	NP_001259052.1	Gene:	Rad23 / 43785	FlyBaseID:	FBgn0026777	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_001009680.1	Gene:	Oas1i / 304507	RGDID:	1359379	Length:	382	Species:	Rattus norvegicus

Alignment Length:	370	Identity:	67/370 - (18%)
Similarity:	116/370 - (31%)	Gaps:	134/370 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LKKKIFEERGPEYVAEKQKLIYAGVILTDDRTVGSYNVDEKKFIVVMLTRDSSSSNRNQLSVKES 90
            ||::.|  ||..:.....|::..|.........|..:.|    :||.|
  Rat    42 LKERCF--RGAAHPVRVSKVVKGGSSGKGTTLKGKSDAD----LVVFL----------------- 83

  Fly    91 NKLTSTDDSKQSMPCEEANHTNSPSSTNTEDSVLSRETRPLSSDELIGELAQASLQSRAESNLLM 155
            |.|||.:|.                        |:|.      .|.|.|:.:...:.:.|.:..:
  Rat    84 NNLTSFEDQ------------------------LNRR------GEFIKEIKKQLYEVQRERHFGV 118

  Fly   156 GDEYNQTVLSMVEMGYPREQVERAMAASYNNPERAVEYLINGIPAEEGTFYNRLNESTNPSLIPS 220
            ..|...:       .:|.   .||::...:.|....|...:.:||.:...:..:....:|.:..|
  Rat   119 KFEVQSS-------WWPN---PRALSFKLSAPHLQQEVEFDVLPAYDVLGHVSIYSMPDPQIYAS 173

  Fly   221 -----------GPQPASATSAERSTESNSDPFEFLRSQPQFLQMRSLIYQNPHLLHAVLQQIGQT 274
                       |......|..:|:         ||:.:|  .:::|||....:..|...:::|:.
  Rat   174 LIRKCMYLGKEGEFSTCFTELQRN---------FLKRRP--TKLKSLIRLVKYWYHLCKEKLGKP 227

  Fly   275 NP-----------------------------ALLQLISENQD------AFLNMLNQPIDRESESG 304
            .|                             |:|:||.:.|:      .:.|..:|.:.....:.
  Rat   228 LPPQYALELLTVYAWERGNGFVDFETAQGFRAVLELIIKYQELRIYWTTYYNFQHQEVSNYLHTQ 292

  Fly   305 ATVPPVSNARI-PSTLDNVDLFSPDLEVATS---AQRSAAGTSAA 345
            .|       || |..||..|   |...:|.|   ..|..||.:||
  Rat   293 LT-------RIRPVILDPAD---PTGNIAGSNPEGWRRLAGEAAA 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rad23	NP_001259052.1	rad23	1..413	CDD:273167	67/370 (18%)
		RAD23_N	1..76	CDD:176400	12/49 (24%)
		UBA1_Rhp23p_like	153..199	CDD:270561	6/45 (13%)
		XPC-binding	242..296	CDD:286376	15/88 (17%)
		UBA2_HR23A	371..411	CDD:270610
Oas1i	NP_001009680.1	NT_2-5OAS_ClassI-CCAase	29..212	CDD:143390	42/243 (17%)
Oas1i	NP_001009680.1	OAS1_C	164..348	CDD:287404	36/185 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900