DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rad23 and Isg15

DIOPT Version :9

Sequence 1:	NP_001259052.1	Gene:	Rad23 / 43785	FlyBaseID:	FBgn0026777	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_001100170.1	Gene:	Isg15 / 298693	RGDID:	1310312	Length:	161	Species:	Rattus norvegicus

Alignment Length:	145	Identity:	30/145 - (20%)
Similarity:	63/145 - (43%)	Gaps:	19/145 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ITIKNLQQQTFTIEFAPEKTVLELKKKIFEERG-PEYVAEKQKLIY-AGVILTDDRTVGSYNVDE 65
            :.:|.|..:.|.:.......:.||||::.::.| |.:   :|:|.: :|.:|.|...:....:..
  Rat     5 LKVKMLGGKEFLVSMTNSMMLSELKKQVAQKSGVPAF---QQRLAHQSGEMLQDGVALIRQGLSS 66

  Fly    66 KKFIVVMLTRDSS------SSNRNQLSVKESNKLTSTDDSKQSMPCEEANHTNSPSSTNTEDSVL 124
            ...:::|:...|.      .:.|.:.:|.|. :||.|   .:.:..:.:.|    ...:.:...|
  Rat    67 GSTVMLMVENCSHPLSILVRNERGRSNVYEV-QLTQT---VEVLMRQVSQH----EQVSQDQFWL 123

  Fly   125 SRETRPLSSDELIGE 139
            |...||:...|.:||
  Rat   124 SFNGRPMEDKEPLGE 138

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rad23	NP_001259052.1	rad23	1..413	CDD:273167	30/145 (21%)
		RAD23_N	1..76	CDD:176400	15/74 (20%)
		UBA1_Rhp23p_like	153..199	CDD:270561
		XPC-binding	242..296	CDD:286376
		UBA2_HR23A	371..411	CDD:270610
Isg15	NP_001100170.1	UBQ	1..78	CDD:294102	15/75 (20%)
		UBQ	3..75	CDD:214563	15/72 (21%)
		UBQ	81..152	CDD:214563	14/66 (21%)
		UBQ	83..156	CDD:294102	14/64 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900