DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Rad23 and Ubqlnl

DIOPT Version :9

Sequence 1:NP_001259052.1 Gene:Rad23 / 43785 FlyBaseID:FBgn0026777 Length:414 Species:Drosophila melanogaster
Sequence 2:NP_001013921.1 Gene:Ubqlnl / 293287 RGDID:1307202 Length:612 Species:Rattus norvegicus


Alignment Length:481 Identity:93/481 - (19%)
Similarity:167/481 - (34%) Gaps:129/481 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 QQTFTIEFAPEKTVLELKKKIFEERGPEYVAEKQKLIYA--GVILTDDRTVGSYNVDEKKFIVVM 72
            |..||:  |.:.:|.:.|    |:....:..:.::|:..  |.:|.|..|:....:.:...|.|:
  Rat    41 QNVFTV--AEDTSVRQFK----EQLSSHFKCQMEQLVLVSMGRLLKDHDTLSQRGITDGHTIHVV 99

  Fly    73 LTRDSSSSNRNQLSVKESNKLTSTDDSKQSMPCEEANHTNSPSSTNTEDSVLSRETRPLSSDELI 137
            :   .|......|:....|.||:.       ||.:..:....|||..:.:.:|            
  Rat   100 I---KSKHGSRSLTHSFRNLLTNN-------PCHQDRNPKGNSSTVCQSAGMS------------ 142

  Fly   138 GELAQASLQSRAESNLLMGDEYNQTVLSMVEMGYPREQVERAMAASYNNPERAVEYLINGIPAEE 202
                    :::.||::||..:.::......|:|.| ||:|:.:.........:..:.::.:|.|.
  Rat   143 --------ETKVESSILMEPDASKVCTQDPEVGSP-EQIEQMLETLCVQRLLSNMFFMHQLPPEH 198

  Fly   203 GTFYNRLNESTNPSL-------------------------IPSGPQPASATSAERSTESNSDPFE 242
            ....:.:.:  ||.:                         |....|||.  :.|.:.  |..|:.
  Rat   199 PDMQDLIQQ--NPEVSHLLDNSEILCQTLELARHLAIIQEIMQIQQPAQ--NPEHTL--NPQPYL 257

  Fly   243 FLRSQPQFLQMRSLIYQ--NPHLLHA-------------------VLQQIGQTNPALLQLISENQ 286
            .|.:.|....:....|.  |.|:|:.                   ||:|: || |:|.|...:.|
  Rat   258 GLETIPNGNIVLGQGYDNFNDHMLNGVHVHDLLEDDSFTALLAEQVLEQV-QT-PSLCQPPPQEQ 320

  Fly   287 DAFLNMLNQPIDRESESGATVPPVSNARIPSTLDNVDLFSPDLEVATSAQRSAAGTSAAHQ---- 347
            ...|:. :|.|...|....|.|..:|.   :|.:|....:|    |.:|.:..:...|..|    
  Rat   321 WGQLSS-SQVIFANSCGFLTTPTEANL---NTTNNASRENP----AIAATQGQSNVCAVQQPTEI 377

  Fly   348 ----------------------SGSAAD--NEDLEQPLGVSTIRLNRQDKDAIERLKALGFPEAL 388
                                  .||:|.  .|||:|....|:.::.|.....:.....:.....|
  Rat   378 PSLCTIPVIQEPREGDKDTTIPQGSSAQWLEEDLQQSEEQSSSQITRSMIQLLRTHPHMAAEMLL 442

  Fly   389 VLQAYFACEKNEEQAANFLLSSSFDD 414
            :|......|:..:|.|..|.||...|
  Rat   443 LLNPPQLNEQWRQQTATPLQSSQLSD 468

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rad23NP_001259052.1 rad23 1..413 CDD:273167 92/478 (19%)
RAD23_N 1..76 CDD:176400 14/67 (21%)
UBA1_Rhp23p_like 153..199 CDD:270561 8/45 (18%)
XPC-binding 242..296 CDD:286376 16/74 (22%)
UBA2_HR23A 371..411 CDD:270610 7/39 (18%)
UbqlnlNP_001013921.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..25
UBQ 31..101 CDD:214563 14/68 (21%)
UBQ 31..101 CDD:294102 14/68 (21%)
UBA_PLICs 569..606 CDD:270582
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5272
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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