DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rad23 and Ubqlnl

DIOPT Version :9

Sequence 1:	NP_001259052.1	Gene:	Rad23 / 43785	FlyBaseID:	FBgn0026777	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_941026.2	Gene:	Ubqlnl / 244179	MGIID:	2685336	Length:	610	Species:	Mus musculus

Alignment Length:	375	Identity:	84/375 - (22%)
Similarity:	142/375 - (37%)	Gaps:	90/375 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 EKQKLIYAGVILTDDRTVGSYNVDEKKFIVVML-----TRDSSSSNRNQLSVKESNKLTSTDDSK 100
            |:..|::.|.:|.|..|:....:.:...|.|::     .|..:.|.||.::   :|......:.|
Mouse    68 EQLVLVFMGRLLKDHDTLSQRGITDGHIIHVVIKSKHGPRSLAHSFRNLVT---NNPCHQDRNPK 129

  Fly   101 --QSMPCEEANHTNSPSSTNTEDSVLSRETRPLSSDEL--IGELAQAS--LQSRAESNLLMGDEY 159
              .||.|:.|    ..:.|..|.|:|.....|....|.  :|.|...:  |::....:||...::
Mouse   130 GNSSMVCQSA----GMNETKVESSLLMEPEAPKVGTESPEVGSLEHIAQVLENLCVQSLLSNMDF 190

  Fly   160 NQTVLSM-VEMGYPREQVERAMAASYNNPERAVEYLINGIP--------AEEGTFYNRLNESTNP 215
               |..| .|..|..|.:::       |||  |.:|::...        .........:.:...|
Mouse   191 ---VHQMPPEQPYMEELIQQ-------NPE--VSHLLDNSEILCQTLELVRHLAIIQEIMQIQQP 243

  Fly   216 SLIPSGPQPASATSAERSTESNSDPFEFLRSQPQFLQM--RSLIYQNPHLLHAVLQQI-GQTNPA 277
            :..|..|             .||.||..|.:.|.....  :|.:..|.|:|:.|...: |....|
Mouse   244 AQNPEYP-------------PNSQPFLGLETVPNGNNHLGQSYVNNNDHMLNGVPDLLEGNCFTA 295

  Fly   278 LL--QLISENQDAFLNMLNQPIDRE-------------SESGATVPPVSNARIPSTLDNVDLFSP 327
            ||  |::.:.|..   .|:||:.:|             :..|.:....:|| .|:..:||...:|
Mouse   296 LLDEQVLEQVQTP---SLSQPLPQEQWDQLSSSQVIYANSCGLSSITPTNA-TPNHTNNVSRENP 356

  Fly   328 DLEVATSAQRSAAGTSAAHQSGSAADNEDLEQPLGVSTIRLNRQ---DKD 374
            .: |||..           ||...|..:..|.|: :.||.:|::   |||
Mouse   357 AI-VATQG-----------QSNVCAVQQPAEIPV-LPTISINQKPQVDKD 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rad23	NP_001259052.1	rad23	1..413	CDD:273167	84/375 (22%)
		RAD23_N	1..76	CDD:176400	8/39 (21%)
		UBA1_Rhp23p_like	153..199	CDD:270561	12/46 (26%)
		XPC-binding	242..296	CDD:286376	14/58 (24%)
		UBA2_HR23A	371..411	CDD:270610	3/7 (43%)
Ubqlnl	NP_941026.2	UBQ	31..101	CDD:214563	8/32 (25%)
		UBQ	31..101	CDD:294102	8/32 (25%)
		UBA_PLICs	567..606	CDD:270582
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900