DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syt7 and Syt6

DIOPT Version :9

Sequence 1:	NP_726557.3	Gene:	Syt7 / 43783	FlyBaseID:	FBgn0039900	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	XP_038958947.1	Gene:	Syt6 / 60565	RGDID:	62012	Length:	535	Species:	Rattus norvegicus

Alignment Length:	393	Identity:	148/393 - (37%)
Similarity:	218/393 - (55%)	Gaps:	60/393 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 RHKRSQLQFIEPNEDEESSSYSLRAAQDI----VDSGN--PPTKPQVPVAHAITTPLQNNINRKL 89
            ||.:.|.|..||......:|:.....:.:    ||.||  ||...:.|.:
  Rat   161 RHTKLQRQTTEPASSTRHTSFKRHLPRQMHVSSVDYGNELPPAAAEQPTS--------------- 210

  Fly    90 NGFLSLRTPLIGGSGASQTKPQIISSVGNPGDGTTKDSANKSISMTDMYLDSTDPSENVGQIHFS 154
                      ||     :.||::.......||....::|                 ::.|:|:||
  Rat   211 ----------IG-----RIKPELYKQKSVDGDEAKSEAA-----------------KSCGKINFS 243

  Fly   155 LEYDFQNTTLILKVLQGKELPAKDLSGTSDPYVRVTLLPDKKHRLETKIKRRTLNPRWNETFYFE 219
            |.||:::.|||:::|:..:|||||..|:|||||::.||||:|.:|:|::.|:||||.::|.|:|.
  Rat   244 LRYDYESETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFP 308

  Fly   220 GFPIQKLQSRVLHLHVFDYDRFSRDDSIGEVFLP-LCQV-DFAGKQSFWKALKPPAKDK--CGEL 280
             .|.::|..|.|||.|||:|||||.|.||||.|. |.:. |.:.:.|.||.::....:.  .||:
  Rat   309 -VPYEELADRKLHLSVFDFDRFSRHDMIGEVILDNLFEASDLSRETSIWKDIQYATSESVDLGEI 372

  Fly   281 LSSLCYHPSNSILTLTLIKARNLKAKDINGKSDPYVKVWLQFGDKRVEKRKTPIFTCTLNPVFNE 345
            :.||||.|:...||||:||.|||||.||.|.|||||||.|....:|::|:||.|...|||||:||
  Rat   373 MFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNE 437

  Fly   346 SFSFNVPWEKIRECSLDVMVMDFDNIGRNELIGRILLAGKNGSGASETKHWQDMISKPRQTVVQW 410
            :..|::|.|.:.:.||.:.|||:|.:|.||:|| :...|.:..|... .||.:|::.||:.:..|
  Rat   438 AIIFDIPPENMDQVSLLISVMDYDRVGHNEIIG-VCRVGISAEGLGR-DHWNEMLAYPRKPIAHW 500

  Fly   411 HRL 413
            |.|
  Rat   501 HCL 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syt7	NP_726557.3	C2A_Synaptotagmin-7	147..271	CDD:176032	62/125 (50%)
Syt7	NP_726557.3	C2B_Synaptotagmin-7	277..414	CDD:176050	65/137 (47%)
Syt6	XP_038958947.1	C2A_Synaptotagmin-1-5-6-9-10	237..361	CDD:176031	62/124 (50%)
Syt6	XP_038958947.1	C2B_Synaptotagmin-3-5-6-9-10	370..503	CDD:176048	64/134 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D394604at33208
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920