Protein Alignment Syt7 and syt12

DIOPT Version :10

• Sequence 1: NP_726557.3
• Gene: Syt7 / 43783
• FlyBaseID: FBgn0039900
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_001122205.1
• Gene: syt12 / 566397
• ZFINID: ZDB-GENE-081022-147
• Length: 420
• Species: Danio rerio
• Alignment Length: 431
• Identity: 118/431 - (27%)
• Similarity: 195/431 - (45%)
• Gaps: 62/431 - (14%)

  Fly     9 CLAILGLIITIALFLAGGYLWWRHKRSQLQFIEPN----------EDEESSSYSLRAAQDIVDSG 63
            ||.:.|.::..|:.:..  ||..:|..  .|..|:          :::..||:| ...|..|.:.
Zfish    25 CLFVFGFLVLFAVVIVN--LWRLYKSG--TFPTPSPFPNFHYRYLQEKYGSSHS-EVRQKRVAAC 84

  Fly    64 N---PPTKPQVPVAHAITTPLQNNINRKLNGFLSLRTPLIGGSGASQTKPQIISSVGNPGDGTTK 125
            |   ..:..:.|....:.||   :..|.| |.|.|.:..:..||.
Zfish    85 NQRRASSASRKPSLQLLDTP---DGLRDL-GTLELMSRELDQSGG-------------------- 125

  Fly   126 DSANKSISMTDMYLDSTDPSE-----NVGQIHFSLEYDFQNTTLILKVLQGKELPAKDLSGTSDP 185
             |.|:|:|...:...|:....     .|||:..:||.|.:.:.|::.:.|||:|..|:.......
Zfish   126 -SLNRSVSSESLCSISSVAQTFGHDFTVGQLEVTLELDTRASLLLVALHQGKDLLEKEEENFPGC 189

  Fly   186 YVRVTLLPDKKHRLETKIKRRTLNPRWNETFYFEGFPIQ--KLQSRVLHLHVFDYDRFSRDDSIG 248
            ::.|||:|.:.:...|:::|......::|.|   ..|::  .|:...|....|..|...|:.:.|
Zfish   190 FITVTLVPQQINLGATQVQRNAFTVVFDERF---SVPLESVNLEENSLRFSTFGVDSDERNITAG 251

  Fly   249 EVFLPLCQVDFAGKQ-SFWKALKP--PAKDKCGELLSSLCYHPSNSILTLTLIKARNLKAKDING 310
            ...|.|..:|...:. :.|..|:.  .|.|..||:|.||.|.|:...||:.:.||:||..  .||
Zfish   252 VAELKLSDLDLPYRPFNAWLYLQDINKAVDAVGEILLSLSYLPTAERLTVVIAKAKNLVW--TNG 314

  Fly   311 K--SDPYVKVWLQFGDKRVEKRKTPIFTCTLNPVFNESFSFNVPWEKIRECSLDVMVMDFDNIGR 373
            |  :||:|||:|....:::.|:||.|.....||:|||:..|:||...:::.||.|.|.:....||
Zfish   315 KTTADPFVKVYLLQDGRKISKKKTSIKRDDTNPIFNEAMIFSVPAIVLQDLSLRVTVAESTEDGR 379

  Fly   374 NELIGRILLAGKNGSGASETKHWQDMISKPRQTVVQWHRLK 414
            .|.:|.::: |...||...| ||..|::..|:.|..||.|:
Zfish   380 GENVGHVII-GPEASGMGIT-HWNQMLATLRKPVSMWHPLR 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt7	NP_726557.3	C2A_Synaptotagmin-7	147..271	CDD:176032	32/126 (25%)
		C2B_Synaptotagmin-7	277..414	CDD:176050	53/138 (38%)
syt12	NP_001122205.1	C2	151..262	CDD:472691	29/113 (26%)
		C2B_Synaptotagmin-12	283..418	CDD:176051	53/138 (38%)