Protein Alignment Syt7 and Syt8

DIOPT Version :10

• Sequence 1: NP_726557.3
• Gene: Syt7 / 43783
• FlyBaseID: FBgn0039900
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: XP_006508695.1
• Gene: Syt8 / 55925
• MGIID: 1859867
• Length: 402
• Species: Mus musculus
• Alignment Length: 302
• Identity: 100/302 - (33%)
• Similarity: 155/302 - (51%)
• Gaps: 19/302 - (6%)

  Fly   120 GDGTTKDSANKSISMTDMYLDSTDP----SENVGQIHFSLEYDFQNTTLILKVLQGKELPAKDLS 180
            |.|:.::|....:...|  :|..:|    .:..|::..||||||.:..:.:.:.|...|.|:
Mouse    91 GLGSARNSTTTHLVQPD--VDCLEPCSGGDQQWGRLLLSLEYDFGSQEIRVGLRQAGNLKAE--- 150

  Fly   181 GTSDPYVRVTLLPDKKHRLETKIKRRTLNPRWNETFYFEGFPIQKLQSRVLHLHVFDYDRFSRDD 245
            ||:|||..|::......|.|||:.|.||:|.:.||..|. .|..:|....|.:.::|:.|||..:
Mouse   151 GTADPYAWVSVSTQSGRRHETKVHRGTLSPMFEETCCFL-VPPAELPKATLKVQLWDFKRFSEHE 214

  Fly   246 SIGEVFLPLCQVDFAGKQSFWKALKPPA---KDKCGELLSSLCYHPSNSILTLTLIKARNLKAKD 307
            .:||:.|||..||.......|..|.||.   .::.|||..||.|.||:..||:.:::||.|..
Mouse   215 PLGELQLPLGTVDLQHVLESWYQLGPPGTTEPEQMGELCFSLRYVPSSGSLTVVVLEARGLNP-- 277

  Fly   308 INGKSDPYVKVWLQFGDKRVEKRKTPIFTCTLNPVFNESFSFNVPWEKIRECSLDVMVMDFDNIG 372
              |.::.|||:.|....::.:|.||.....|..|.|||:|.|.||..:::...|.:.|.......
Mouse   278 --GLAEAYVKIQLMLNQRKWKKSKTSSKKGTTTPYFNEAFVFLVPVSQLQSVDLVLAVWARGLQL 340

  Fly   373 RNELIGRILLAGKNGSGASETKHWQDMISKPRQTVVQWHRLK 414
            |.|.:|::|| |...|| ...:||.||::..|:.:.|||.|:
Mouse   341 RTEPVGKVLL-GSRASG-QPLQHWADMLAHARRPIAQWHHLR 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt7	NP_726557.3	C2A_Synaptotagmin-7	147..271	CDD:176032	43/123 (35%)
		C2B_Synaptotagmin-7	277..414	CDD:176050	48/136 (35%)
Syt8	XP_006508695.1	C2	122..240	CDD:472691	43/121 (36%)
		C2	249..379	CDD:472691	48/135 (36%)