DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syt7 and syt5b

DIOPT Version :9

Sequence 1:	NP_726557.3	Gene:	Syt7 / 43783	FlyBaseID:	FBgn0039900	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_001018382.2	Gene:	syt5b / 553567	ZFINID:	ZDB-GENE-050522-134	Length:	446	Species:	Danio rerio

Alignment Length:	300	Identity:	131/300 - (43%)
Similarity:	191/300 - (63%)	Gaps:	12/300 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 GDGTTKDSANKSISMTDMYLDSTDPSENVGQIHFSLEYDFQNTTLILKVLQGKELPAKDLSGTSD 184
            |.|..||...|....     :..:..||:|::.|||:|:|.:..||:.:||.::|.|.|:.||||
Zfish   144 GQGEQKDEGEKKEGE-----EQKEEHENLGKLEFSLDYNFTDAQLIVGILQAQDLAAMDIGGTSD 203

  Fly   185 PYVRVTLLPDKKHRLETKIKRRTLNPRWNETFYFEGFPIQKLQSRVLHLHVFDYDRFSRDDSIGE 249
            |||:|.||||||.:.|||::|:.|.|.:||||.|: .|..:|..:.|.|.|||:|||.:.|.||:
Zfish   204 PYVKVYLLPDKKKKFETKVQRKNLCPVFNETFIFK-IPYAELGGKTLVLQVFDFDRFGKHDVIGQ 267

  Fly   250 VFLPLCQVDFAGKQSFWKALKPPAK--DKCGELLSSLCYHPSNSILTLTLIKARNLKAKDINGKS 312
            :.:|:..||.|.....|:.|:...|  :|.|::..||.|.|:...||:.:::|:|||..|:.|.|
Zfish   268 IKIPMNCVDLAQPLHEWRELENGEKEEEKLGDVCISLRYVPTAGKLTVNIMEAKNLKKMDVGGLS 332

  Fly   313 DPYVKVWLQFGDKRVEKRKTPIFTCTLNPVFNESFSFNVPWEKIRECSLDVMVMDFDNIGRNELI 377
            |||||:.||...||::|:||.:...||||.|||||||.||:|:|::..|.:.|.|:|.:|.|:.|
Zfish   333 DPYVKIVLQHNGKRLKKKKTTVKKNTLNPYFNESFSFEVPFEQIQKVQLLITVYDYDKLGSNDPI 397

  Fly   378 GRILLA-GKNGSGASETKHWQDMISKPRQTVVQWHRLKPE 416
            |:..:. |..|.|   .:||.||::.||:.|.|||.|:||
Zfish   398 GKTFIGYGATGVG---LRHWSDMLANPRRPVAQWHTLQPE 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syt7	NP_726557.3	C2A_Synaptotagmin-7	147..271	CDD:176032	58/123 (47%)
Syt7	NP_726557.3	C2B_Synaptotagmin-7	277..414	CDD:176050	62/137 (45%)
syt5b	NP_001018382.2	C2A_Synaptotagmin-1-5-6-9-10	166..285	CDD:176031	56/119 (47%)
syt5b	NP_001018382.2	C2B_Synaptotagmin-1	298..432	CDD:176047	62/136 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D394604at33208
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X85
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.920