Protein Alignment Syt7 and SYTL2

DIOPT Version :9

• Sequence 1: NP_726557.3
• Gene: Syt7 / 43783
• FlyBaseID: FBgn0039900
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_996810.2
• Gene: SYTL2 / 54843
• HGNCID: 15585
• Length: 2239
• Species: Homo sapiens
• Alignment Length: 416
• Identity: 104/416 - (25%)
• Similarity: 177/416 - (42%)
• Gaps: 60/416 - (14%)

  Fly    38 QFIEPNEDEESSSYSLRAAQDIVDSGNPPTKPQVPVAHAITTPLQNNINRKLNGFLSLRTPLIGG 102
            :.:...||:|.........:.:......||:|..|.:|   ......:::.:..||...:.....
Human  1820 ELVRSAEDDEKPDQKPVTNECVPRISTVPTQPDNPFSH---PDKLKRMSKSVPAFLQDESDDRET 1881

  Fly   103 SGASQTKPQIISSVGNPGDGTTKDSAN-----KSISMTDMYLDSTD--PSENVGQIHFSLEYDFQ 160
            ..||::..|:.....:|...|...|::     .|:|.:.|.:.|.|  ..|..|.|.|::||...
Human  1882 DTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVES 1946

  Fly   161 NTTLILKVLQGKELPAKDL-SGTSDPYVRVTLLPD--KKHRLETKIKRRTLNPRWNETFYFEGFP 222
            ...|.:.|.|.|:|.|.|: ...|||||:..||||  |..:.:|.:.::||||.:||...::
Human  1947 LKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYK--- 2008

  Fly   223 IQK--LQSRVLHLHVFDYDRFSRDDSIGEVFLPLCQVDFAGKQS---FWKALK----PPA--KDK 276
            |:|  |:::.|:|.::..|.|.|:..:|||.|.|...|:..||:   .|..||    |.|  .:.
Human  2009 IEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAEN 2073

  Fly   277 CGELLSSLCYHPS-----------------NSILTLTLIKARNLKAKDINGKSDPYVKVWLQFGD 324
            .||:..:|.|.|.                 ...|.|.|::..:|.:         :||..:....
Human  2074 RGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNS---------FVKCTILPDT 2129

  Fly   325 KRVEKRKTPIFTCTLNPVFNESFSFN--VPWEKIRECSLDVMVMDFDNIGRNELIGRILLAGKNG 387
            .|..::||.....|.||:||.:..::  .| |.:.|..:::.|.|...: .|:.:|.:.:....|
Human  2130 SRKSRQKTRAVGKTTNPIFNHTMVYDGFRP-EDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTG 2192

  Fly   388 SGASETKHWQDMISKPRQTVVQWHRL 413
            ........|.|..|   :.|..|.::
Human  2193 KSYGTEVDWMDSTS---EEVALWEKM 2215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt7	NP_726557.3	C2A_Synaptotagmin-7	147..271	CDD:176032	48/135 (36%)
		C2B_Synaptotagmin-7	277..414	CDD:176050	32/156 (21%)
SYTL2	NP_996810.2	PHD_SF	5..>41	CDD:328929
		C2	1934..2061	CDD:326325	46/129 (36%)
		C2B_SLP_1-2-3-4	2074..2230	CDD:175987	32/156 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910