Protein Alignment Syt7 and SYT17

DIOPT Version :10

• Sequence 1: NP_726557.3
• Gene: Syt7 / 43783
• FlyBaseID: FBgn0039900
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: XP_047290159.1
• Gene: SYT17 / 51760
• HGNCID: 24119
• Length: 500
• Species: Homo sapiens
• Alignment Length: 391
• Identity: 135/391 - (34%)
• Similarity: 210/391 - (53%)
• Gaps: 46/391 - (11%)

  Fly    43 NEDEESSSYSLRAAQDIVDSGNPPTKPQVPVAHAITTPLQNNINRKLNGFLSLRTPLIGGSGASQ 107
            :.|...|:|||......::| ..|:.|.:.:     .|::       .|.||.:...|
Human   121 SSDTSKSTYSLTRRISSLES-RRPSSPLIDI-----KPIE-------FGVLSAKKEPI------- 165

  Fly   108 TKPQIISSVGNPGDGTTK--------DSANKSI-SMTDMYLDSTDPSENVGQIHFSLEYDFQNTT 163
             :|.::....||.|...|        ||.:..: |:||..:.|   ...:|.:|||.:||..:..
Human   166 -QPSVLRRTYNPDDYFRKFEPHLYSLDSNSDDVDSLTDEEILS---KYQLGMLHFSTQYDLLHNH 226

  Fly   164 LILKVLQGKELP--------AKDLSGTSDPYVRVTLLPDKKHRLETKIKRRTLNPRWNETFYFEG 220
            |.::|::.::||        .:|:: .|:|||::.||||:|:..:|.:||:|..|.:.|.:.||
Human   227 LTVRVIEARDLPPPISHDGSRQDMA-HSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFE- 289

  Fly   221 FPIQKLQSRVLHLHVFDYDRFSRDDSIGEVFLPLCQVDFAGKQSFWKALKPPAKD--KCGELLSS 283
            .|..:.|.|.|.|.|.|:|:|||...||:|.:|||:||......:||||.|.:::  :.||||.|
Human   290 IPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVPLCEVDLVKGGHWWKALIPSSQNEVELGELLLS 354

  Fly   284 LCYHPSNSILTLTLIKARNLKAKDINGKSDPYVKVWLQFGDKRVEKRKTPIFTCTLNPVFNESFS 348
            |.|.||...|.:.:|:|:.|...|::..|||:||:.|..|.|.|:.:||.....|::|.:|||||
Human   355 LNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFS 419

  Fly   349 FNVPWEKIRECSLDVMVMDFDNIGRNELIGRILLAGKNGSGASETKHWQDMISKPRQTVVQWHRL 413
            |.||.|::...||...|...:....|:.||||:: |:..||.|||.||:.|::..|..|.|||.|
Human   420 FKVPQEELENASLVFTVFGHNMKSSNDFIGRIVI-GQYSSGPSETNHWRRMLNTHRTAVEQWHSL 483

  Fly   414 K 414
            :
Human   484 R 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt7	NP_726557.3	C2A_Synaptotagmin-7	147..271	CDD:176032	51/131 (39%)
		C2B_Synaptotagmin-7	277..414	CDD:176050	58/136 (43%)
SYT17	XP_047290159.1	C2A_Synaptotagmin-15-17	212..340	CDD:176036	51/129 (40%)
		C2B_Synaptotagmin-17	349..483	CDD:176055	58/134 (43%)