DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syt7 and Syt2

DIOPT Version :9

Sequence 1:	NP_726557.3	Gene:	Syt7 / 43783	FlyBaseID:	FBgn0039900	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	XP_038946276.1	Gene:	Syt2 / 24805	RGDID:	3804	Length:	499	Species:	Rattus norvegicus

Alignment Length:	298	Identity:	136/298 - (45%)
Similarity:	198/298 - (66%)	Gaps:	6/298 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 GTTKDSANKSISMTDMYLDSTDPSENVGQIHFSLEYDFQNTTLILKVLQGKELPAKDLSGTSDPY 186
            |...|.|...::..:...:.....||:|::.|||:||||...|.:.|||..||||.|:.||||||
  Rat   194 GQDDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPY 258

  Fly   187 VRVTLLPDKKHRLETKIKRRTLNPRWNETFYFEGFPIQKLQSRVLHLHVFDYDRFSRDDSIGEVF 251
            |:|.||||||.:.|||:.|:||||.:||||.|: .|.|:|..:.|.:.::|:||||:.|.||||.
  Rat   259 VKVFLLPDKKKKYETKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDRFSKHDIIGEVK 322

  Fly   252 LPLCQVDFAGKQSFWKALKPPAK---DKCGELLSSLCYHPSNSILTLTLIKARNLKAKDINGKSD 313
            :|:..||.......|:.|:...|   :|.|::.:||.|.|:...||:.:::|:|||..|:.|.||
  Rat   323 VPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSD 387

  Fly   314 PYVKVWLQFGDKRVEKRKTPIFTCTLNPVFNESFSFNVPWEKIRECSLDVMVMDFDNIGRNELIG 378
            ||||:.|....||::|:||.:...||||.|||||||.:|:|:|::..:.|.|:|:|.:|:||.||
  Rat   388 PYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIG 452

  Fly   379 RILLAGKNGSGASETKHWQDMISKPRQTVVQWHRLKPE 416
            :|.: |.|.:| :|.:||.||::.||:.:.|||.||||
  Rat   453 KIFV-GSNATG-TELRHWSDMLANPRRPIAQWHSLKPE 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syt7	NP_726557.3	C2A_Synaptotagmin-7	147..271	CDD:176032	64/123 (52%)
Syt7	NP_726557.3	C2B_Synaptotagmin-7	277..414	CDD:176050	62/136 (46%)
Syt2	XP_038946276.1	Syt2_N	81..193	CDD:409249
		C2A_Synaptotagmin-1-5-6-9-10	219..341	CDD:176031	63/122 (52%)
		C2B_Synaptotagmin-1	351..486	CDD:176047	62/136 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D394604at33208
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920