Protein Alignment Syt7 and Sytl5

DIOPT Version :9

• Sequence 1: NP_726557.3
• Gene: Syt7 / 43783
• FlyBaseID: FBgn0039900
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_808372.1
• Gene: Sytl5 / 236643
• MGIID: 2668451
• Length: 753
• Species: Mus musculus
• Alignment Length: 516
• Identity: 126/516 - (24%)
• Similarity: 191/516 - (37%)
• Gaps: 170/516 - (32%)

  Fly    45 DEES------SSYSLRAAQDIVDSGNPPT-KPQVPVAHAITTPLQNNINRKLNGF---LSLR--- 96
            |:|:      ||||        :.|.|.| :..||.||::|     :||.:.:||   ::|.
Mouse   240 DQEAGRRTSKSSYS--------NGGIPVTQRSPVPSAHSVT-----SINSREHGFENSMALATIE 291

  Fly    97 ----------------TPLIGGSGAS----QTKPQI---------------ISSVGNPG------ 120
                            ||.|..||.|    :::.::               |.|...||
Mouse   292 NTCEELTKSHRRNTSGTPSIAVSGTSLSSERSRSEVDLSESFAEDLEDTSSIRSRSVPGALDKDL 356

  Fly   121 -------DGT------------------------------------TKDSANKSI-SMTDMYLDS 141
                   ||.                                    ..||...|: ||..:|.::
Mouse   357 NSLEDTEDGVDLVSSRFSANTHSLASGLSTNSQAGSDRKRSYLNVPDADSDTTSLNSMMSVYSET 421

  Fly   142 TDPSENV---GQIHFSLEYDFQNTTLILKVLQGKELPAKD-LSGTSDPYVRVTLLPDKKHRLETK 202
            .|.. ||   |:|...:.|.::...|.:.|...:.|...| ....:|.||:..|||||....:.|
Mouse   422 GDYG-NVKVTGEILLHISYCYKTGGLYIFVKSCRNLATGDEKKQRTDAYVKSYLLPDKSRNNKRK 485

  Fly   203 IKRRT-LNPRWNETFYFEGFPIQKLQSRVLHLHVFDYDRFSRDDSIGEVFLPLCQVDFAGKQSFW 266
            .|.|| .||.:|||..:. ....:|::|.|.|.|:.||||.|:..:|||.:.....:|......|
Mouse   486 TKIRTGTNPEFNETLKYT-ISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIAFDSWNFENPCDEW 549

  Fly   267 KALKPPAK-------DKCGELLSSLCYHP-----------------------------SNSILTL 295
            ..|:|..:       ...|||...|.|.|                             |..||.:
Mouse   550 FVLQPKVELAPDISLQYKGELTIVLRYIPPEENLIFPAGQRQEKKIFKRGKKKESSSISGGILEV 614

  Fly   296 TLIKARNLKAKDINGKSDPYVKVWLQFGDKRVEKRKTPIFTCTLNPVFNESFSFNVPW-EKIREC 359
            .:.||:||.|....|.||.:||.:|...|.:..|.||.:...::||.:|.:|.|:..: :.|:..
Mouse   615 FIKKAKNLTAVKSGGTSDSFVKGYLLPDDNKATKHKTAVVKKSVNPEWNHTFIFSGLYPQDIKNA 679

  Fly   360 SLDVMVMDFDNIGRNELIGRILLAGKNGSGAS-------------ETKHWQDMISKPRQTV 407
            .|::.:.|.:....|..:|.:.|  .:|||.|             |.:.||.|...|..:|
Mouse   680 CLELTIWDKEAFSSNVFLGGVRL--NSGSGMSYGKTVDWMDSHGEEQRLWQKMADNPGTSV 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt7	NP_726557.3	C2A_Synaptotagmin-7	147..271	CDD:176032	42/128 (33%)
		C2B_Synaptotagmin-7	277..414	CDD:176050	45/174 (26%)
Sytl5	NP_808372.1	PHD_SF	11..123	CDD:419867
		FYVE_Slp5	62..108	CDD:277305
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	145..279		16/51 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..359		10/61 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	380..404		0/23 (0%)
		C2A_SLP-4_5	430..553	CDD:175995	39/123 (32%)
		C2B_SLP_1-2-3-4	567..745	CDD:175987	45/174 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910