Protein Alignment Syt7 and Syt11

DIOPT Version :10

• Sequence 1: NP_726557.3
• Gene: Syt7 / 43783
• FlyBaseID: FBgn0039900
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_061274.2
• Gene: Syt11 / 229521
• MGIID: 1859547
• Length: 430
• Species: Mus musculus
• Alignment Length: 452
• Identity: 140/452 - (30%)
• Similarity: 224/452 - (49%)
• Gaps: 92/452 - (20%)

  Fly     5 VLIACLAILGLIITIALFLAGGYLWW--------RHKRSQLQFIE-------------------- 41
            ||:.|::     :|:       ::|.        :||....:||.
Mouse    25 VLVVCVS-----VTV-------FVWTCCHQQAEKKHKTPPYKFIHMLKGISIYPETLSNKKKIIK 77

  Fly    42 -------PNEDEESSSYSLRAAQDIVDSGNPPTKPQVPVAHAITTPLQNNINRKLNGFLSLRTPL 99
                   |..:....:..:.|...::.....|..|. |.:.....|::.:...:|...::..||
Mouse    78 VRRDKDGPRRESGRGNLLINAESGLLSHDKDPRGPS-PASCMDQLPIKRDYGEELRSPMTSLTP- 140

  Fly   100 IGGSGASQTKPQIISSVGNPGDGTTKDSANKSISMTDMYLDSTDPSENV--GQIHFSLEYDFQNT 162
             |.|.|  |.|                               :.|.|:|  |.:.||::|:|...
Mouse   141 -GESKA--TSP-------------------------------SSPEEDVMLGSLTFSVDYNFPKK 171

  Fly   163 TLILKVLQGKELPA-KDLSGTSDPYVRVTLLPDKKHRLETKIKRRTLNPRWNETFYFEGFPIQKL 226
            .|::.:.:...||. .|.:..||||:::|:||||:||::|::.|:||:|.::|||.|.|.|..:|
Mouse   172 ALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQL 236

  Fly   227 QSRVLHLHVFDYDRFSRDDSIGEVFLPLCQVD-FAGKQSFWKALKPPAKDKC---GELLSSLCYH 287
            |..|||..|..:|||||||.||||.:||..|| ..||....:.:......||   |||..||.|.
Mouse   237 QDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLSYQ 301

  Fly   288 PSNSILTLTLIKARNLKAKDINGKS-DPYVKVWLQFGDKRVEKRKTPIFTCTLNPVFNESFSFNV 351
            |....:|:.::|||:|...||.|.| :|||||.:.:|.||:.|:||.:..|||||||||||.:::
Mouse   302 PVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPVFNESFIYDI 366

  Fly   352 PWEKIRECSLDVMVMDFDNIGRNELIGRILLAGKNGSGASETKHWQDMISKPRQTVVQWHRL 413
            |.:.:.:.|::.:|:|||...:||::||::| |.:....|..:||:::...||:.:.:||.|
Mouse   367 PTDLLPDISIEFLVIDFDRTTKNEVVGRLIL-GAHSVTTSGAEHWREVCESPRKPIAKWHSL 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt7	NP_726557.3	C2A_Synaptotagmin-7	147..271	CDD:176032	55/127 (43%)
		C2B_Synaptotagmin-7	277..414	CDD:176050	59/141 (42%)
Syt11	NP_061274.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	79..120		5/41 (12%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	132..152		7/54 (13%)
		C2A_Synaptotagmin-4-11	157..282	CDD:176034	54/124 (44%)
		C2B_Synaptotagmin-4	291..428	CDD:176049	58/138 (42%)