Protein Alignment Syt7 and Syt3

DIOPT Version :9

• Sequence 1: NP_726557.3
• Gene: Syt7 / 43783
• FlyBaseID: FBgn0039900
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_001107588.1
• Gene: Syt3 / 20981
• MGIID: 99665
• Length: 587
• Species: Mus musculus
• Alignment Length: 536
• Identity: 162/536 - (30%)
• Similarity: 240/536 - (44%)
• Gaps: 144/536 - (26%)

  Fly     1 MASIVLIAC-LAILGLIITIALFLAGGYLW--WRHK----------RSQL--------------- 37
            :.|:::..| :.:||    ::||::....|  ||.|          |..|
Mouse    56 LLSVIVTFCGIVLLG----VSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLAPGVGLAGLVGGGGH 116

  Fly    38 ----------------------------QFIEP-----NEDEESS-----SYSLRAAQDIVDSGN 64
                                        :.:||     :|..|.|     ||...|...:|.:|.
Mouse   117 HLGASLGGHPLLGGPHHHGHTAHHPPFAELLEPGGLGGSEPPEPSYLDMDSYPEAAVASVVAAGV 181

  Fly    65 PP--TKPQVP----------------------VAH-------------AITTPL-QNNINRKLNG 91
            .|  |.|::|                      .:|             |:..|| |..:..:.:.
Mouse   182 KPSQTSPELPSEGGTGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTTQADP 246

  Fly    92 FL-----SLRTPLIGGSGAS----QTKPQIISSV---GNPGDGTTKDSANKSISMTDMYLDSTDP 144
            ..     :|..||.||...:    |.||::....   |..|.|                  |.:.
Mouse   247 STEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRGGG------------------SGEA 293

  Fly   145 SENVGQIHFSLEYDFQNTTLILKVLQGKELPAKDLSGTSDPYVRVTLLPDKKHRLETKIKRRTLN 209
            ....|:|.|:|.|.:.:..|::::||..:|||||.:|.|||||::.||||:|.:.:||:.|:|||
Mouse   294 GAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLN 358

  Fly   210 PRWNETFYFEGFPIQKLQSRVLHLHVFDYDRFSRDDSIGEVFLP--LCQVDFAGKQSFWKALKPP 272
            |.:||||.| ..|:.:|..|.||..|:|:|||||.|.||:|.|.  |...:....:..|:.:...
Mouse   359 PIFNETFQF-SVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDILEG 422

  Fly   273 AKDKC--GELLSSLCYHPSNSILTLTLIKARNLKAKDINGKSDPYVKVWLQFGDKRVEKRKTPIF 335
            ..:|.  |||..||||.|:...||:|:|||.||||.|:.|.||||||..|....:|::||||.|.
Mouse   423 GSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIK 487

  Fly   336 TCTLNPVFNESFSFNVPWEKIRECSLDVMVMDFDNIGRNELIGRILLAGKNGSGASETKHWQDMI 400
            ..||||.:||:..|:|..|.:....|.:.|:|:|.||.||:|| :...|...:.....:||.:|:
Mouse   488 KNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIG-VCRVGPEAADPHGREHWAEML 551

  Fly   401 SKPRQTVVQWHRLKPE 416
            :.||:.|..||:|..|
Mouse   552 ANPRKPVEHWHQLVEE 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt7	NP_726557.3	C2A_Synaptotagmin-7	147..271	CDD:176032	55/125 (44%)
		C2B_Synaptotagmin-7	277..414	CDD:176050	61/138 (44%)
Syt3	NP_001107588.1	Cysteine motif. /evidence=ECO:0000269|PubMed:10531343	10..34
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	183..258		10/74 (14%)
		C2A_Synaptotagmin-1-5-6-9-10	297..421	CDD:176031	55/124 (44%)
		C2B_Synaptotagmin-3-5-6-9-10	430..564	CDD:176048	61/134 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D394604at33208
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920