Protein Alignment Syt7 and Syt12

DIOPT Version :10

• Sequence 1: NP_726557.3
• Gene: Syt7 / 43783
• FlyBaseID: FBgn0039900
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_620190.1
• Gene: Syt12 / 191595
• RGDID: 621876
• Length: 421
• Species: Rattus norvegicus
• Alignment Length: 428
• Identity: 126/428 - (29%)
• Similarity: 205/428 - (47%)
• Gaps: 60/428 - (14%)

  Fly    10 LAILGLIITIALFLAGGYLW--WRHKRSQLQFIEPNEDEESSSYSLRAAQDIVDSGNPPTK-PQV 71
            ||:||        :|...||  |    :...|..|:   ...:|..|..|..........| .:|
  Rat    29 LALLG--------IAAVSLWKLW----TSGSFPSPS---PFPNYDYRYLQQKYGEAYVEAKLKRV 78

  Fly    72 PVAHAITTPLQNNINRKLNGFLSLRTPLIGGSGASQTKPQIISSVGNPGD----GTTK-----DS 127
            |..:|..|..:...:||  |.||:....   ...|:..|  :..:|...|    ||.:     ||
  Rat    79 PPWNAQRTTTRGPPSRK--GSLSIEDTF---ESISELGP--LELMGRELDLAPYGTLRKSQSADS 136

  Fly   128 ANKSISMTDMY-LDSTDPSENVGQIHFSLEYDFQNTTLILKVLQGKELPAKDLSGTSDPYVRVTL 191
            .|...|:::.: .|.|     :||:..|::||..:.||.:.|||||:|..::.:.....::||:|
  Rat   137 LNSISSVSNTFGQDFT-----LGQVEVSMDYDGASHTLHVAVLQGKDLLEREEATFESCFMRVSL 196

  Fly   192 LPDKKHRLETKIKRRTLNPRWNETFYFEGFPIQ--KLQSRVLHLHVFDYDRFSRDDSIGEVFLPL 254
            |||::....::|:|...:..::|.|   ..|:.  .|:.:.|...||..|...|:.|.|.|.|.|
  Rat   197 LPDEQIVGISRIQRNAYSIFFDEKF---SVPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKL 258

  Fly   255 CQVD-----FAGKQSFWKALKP--PAKDKCGELLSSLCYHPSNSILTLTLIKARNLKAKDINGKS 312
            ..:|     |:|    |..|:.  .|.|..||:|.||.|.|:...||:.::||:||...:....:
  Rat   259 SVLDLPLQPFSG----WLYLQDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTA 319

  Fly   313 DPYVKVWLQFGDKRVEKRKTPIFTCTLNPVFNESFSFNVPWEKIRECSLDVMVMDFDNIGRNELI 377
            ||:|||:|....:::.|:||.:.....||||||:..|:||...:::.||.|.|.:..:.||.:.:
  Rat   320 DPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNV 384

  Fly   378 GRILLA-GKNGSGASETKHWQDMISKPRQTVVQWHRLK 414
            |.:::. |.:|.|   |.||..|::..|:.|..||.::
  Rat   385 GHVIIGPGASGMG---TTHWNQMLATLRRPVSMWHPVR 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt7	NP_726557.3	C2A_Synaptotagmin-7	147..271	CDD:176032	40/130 (31%)
		C2B_Synaptotagmin-7	277..414	CDD:176050	49/137 (36%)
Syt12	NP_620190.1	C2	152..263	CDD:472691	36/118 (31%)
		C2B_Synaptotagmin-12	284..419	CDD:176051	49/137 (36%)