Protein Alignment Syt7 and SYT6

DIOPT Version :9

• Sequence 1: NP_726557.3
• Gene: Syt7 / 43783
• FlyBaseID: FBgn0039900
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_001353153.1
• Gene: SYT6 / 148281
• HGNCID: 18638
• Length: 528
• Species: Homo sapiens
• Alignment Length: 475
• Identity: 165/475 - (34%)
• Similarity: 248/475 - (52%)
• Gaps: 99/475 - (20%)

  Fly     3 SIVLIACLAILGLIITIALFLAGGYLWWRHKRSQLQFIEPNEDEESSSYSLRAAQDIVDSGNPPT 67
            |:.|:|.:.|:..:..:|:||   :|:|:     |.:: |..::|:||.|         |.|||.
Human    57 SVSLLAVVVIVCGVALVAVFL---FLFWK-----LCWM-PWRNKEASSPS---------SANPPL 103

  Fly    68 KPQVPVAHAITTP-LQNNINRKLN-----GFLSLRTPLIGGSGASQTKPQIISSV---------- 116
            :       |:.:| .:.|:..||.     |||.....:      |.|.|.|.:.|
Human   104 E-------ALQSPSFRGNMADKLKDPSTLGFLEAAVKI------SHTSPDIPAEVQMSVKEHIMR 155

  Fly   117 --------GNPGDGTTKDSANKSISMTDMYLDSTD------------------------------ 143
                    ..|...|...|..:.:. ..|::.|.|
Human   156 HTRLQRQTTEPASSTRHTSFKRHLP-RQMHVSSVDYGNELPPAAEQPTSIGRIKPELYKQKSVDG 219

  Fly   144 ------PSENVGQIHFSLEYDFQNTTLILKVLQGKELPAKDLSGTSDPYVRVTLLPDKKHRLETK 202
                  .:::.|:|:|||.||::..|||:::|:..:|||||..|:|||||::.||||:|.:|:|:
Human   220 EDAKSEATKSCGKINFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTR 284

  Fly   203 IKRRTLNPRWNETFYFEGFPIQKLQSRVLHLHVFDYDRFSRDDSIGEVFLP-LCQV-DFAGKQSF 265
            :.|:||||.::|.|:|. .|.::|..|.|||.|||:|||||.|.||||.|. |.:. |.:.:.|.
Human   285 VHRKTLNPTFDENFHFP-VPYEELADRKLHLSVFDFDRFSRHDMIGEVILDNLFEASDLSRETSI 348

  Fly   266 WKALKPPAKDK--CGELLSSLCYHPSNSILTLTLIKARNLKAKDINGKSDPYVKVWLQFGDKRVE 328
            ||.::....:.  .||::.||||.|:...||||:||.|||||.||.|.|||||||.|....:|::
Human   349 WKDIQYATSESVDLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLK 413

  Fly   329 KRKTPIFTCTLNPVFNESFSFNVPWEKIRECSLDVMVMDFDNIGRNELIGRILLAGKNGSGASET 393
            |:||.|...|||||:||:..|::|.|.:.:.||.:.|||:|.:|.||:|| :...|....|...
Human   414 KKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIG-VCRVGITAEGLGR- 476

  Fly   394 KHWQDMISKPRQTVVQWHRL 413
            .||.:|::.||:.:..||.|
Human   477 DHWNEMLAYPRKPIAHWHSL 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt7	NP_726557.3	C2A_Synaptotagmin-7	147..271	CDD:176032	62/125 (50%)
		C2B_Synaptotagmin-7	277..414	CDD:176050	65/137 (47%)
SYT6	NP_001353153.1	Cysteine motif. /evidence=ECO:0000250|UniProtKB:O35681	12..38
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	157..178		3/20 (15%)
		C2A_Synaptotagmin-1-5-6-9-10	230..354	CDD:176031	62/124 (50%)
		C2B_Synaptotagmin-3-5-6-9-10	363..496	CDD:176048	64/134 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D394604at33208
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920