DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Syt7 and sytl3

DIOPT Version :9

Sequence 1:	NP_726557.3	Gene:	Syt7 / 43783	FlyBaseID:	FBgn0039900	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	XP_021324208.1	Gene:	sytl3 / 101882017	ZFINID:	ZDB-GENE-040724-150	Length:	581	Species:	Danio rerio

Alignment Length:	233	Identity:	61/233 - (26%)
Similarity:	92/233 - (39%)	Gaps:	33/233 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 INRKLNGFLSLRTPLIGGSGASQTKPQIISSVGNPGDGTTKDSA--------NKSISMTDMYLDS 141
            |||.|....||  |::..:.::.|....::.     |..:..||        |.|..|..:..::
Zfish   242 INRALCKVPSL--PILSTAQSTSTSTLCLTD-----DDVSSTSAYSDDQRDSNSSTGMDSVLFEN 299

  Fly   142 TDPSENVGQIHFSLEYDFQNTTLILKVLQGKELPAKDLSGTSDPYVRVTLLPDKKHRLETKIK-R 205
            |  ....|:|...|.|:.:.:.|.:.:...:.|..:|......|||.|.|||.|.|..:.|.. |
Zfish   300 T--ISVTGEIEVVLAYNNRTSCLEITIKACRNLMFRDTKKKCHPYVNVCLLPKKCHNFKMKTAVR 362

  Fly   206 RTLNPRWNETFYFEGFPIQKLQSRVLHLHVFDYDRFSRDDSIGEVFLPLCQVDFA---GKQSFWK 267
            :..||.:||||... .....|.|.||.|.|:......|...:||..:.|..:|..   .::|...
Zfish   363 KGKNPVYNETFTCV-LSADLLSSAVLQLSVWHSRGLKRRLFLGETLIRLADMDLEDTDSQRSLCC 426

  Fly   268 ALKPPAKDKCGE---------LLSSLCYH--PSNSILT 294
            .|.|.|....|:         ||....:|  |.|:..|
Zfish   427 KLNPKAPQLGGDAELQFTSVLLLIQAQFHTLPHNNTQT 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syt7	NP_726557.3	C2A_Synaptotagmin-7	147..271	CDD:176032	37/127 (29%)
Syt7	NP_726557.3	C2B_Synaptotagmin-7	277..414	CDD:176050	7/29 (24%)
sytl3	XP_021324208.1	PHD_SF	27..134	CDD:328929
		FYVE_like_SF	73..120	CDD:333710
		C2	304..429	CDD:326325	36/125 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910