DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syt7 and syt1

DIOPT Version :9

Sequence 1:	NP_726557.3	Gene:	Syt7 / 43783	FlyBaseID:	FBgn0039900	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	XP_017947750.1	Gene:	syt1 / 100037879	XenbaseID:	XB-GENE-5752629	Length:	425	Species:	Xenopus tropicalis

Alignment Length:	327	Identity:	142/327 - (43%)
Similarity:	205/327 - (62%)	Gaps:	21/327 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 GGSGASQTKPQIISSVGNPGDGTTKDSANK------SISMTDMYLDSTDPS--ENVGQIHFSLEY 157
            ||..|...|.  :..:|.    |.||.|.|      ...:||.. |...|.  |.:|::.:||:|
Frog    98 GGKNAINMKD--VKDLGK----TMKDQALKDDDDDAETGLTDGE-DKEQPKEVEKLGKLQYSLDY 155

  Fly   158 DFQNTTLILKVLQGKELPAKDLSGTSDPYVRVTLLPDKKHRLETKIKRRTLNPRWNETFYFEGFP 222
            ||||..|::.::|..||||.|:.|||||||::.|:||||.:.|||:.|:||||.:||.|.|: .|
Frog   156 DFQNNQLMVGIIQAAELPALDMGGTSDPYVKLFLMPDKKKKFETKVHRKTLNPVFNEQFTFK-VP 219

  Fly   223 IQKLQSRVLHLHVFDYDRFSRDDSIGEVFLPLCQVDFAGKQSFWKALKPPAK---DKCGELLSSL 284
            ..:|..:.|.|.|:|:||||:.|.||:|.:|:..|||......|:.|....|   :|.|::..||
Frog   220 YAELGGKTLVLTVYDFDRFSKHDVIGDVKVPMNTVDFGHVTEEWRDLVSAEKEEQEKLGDICFSL 284

  Fly   285 CYHPSNSILTLTLIKARNLKAKDINGKSDPYVKVWLQFGDKRVEKRKTPIFTCTLNPVFNESFSF 349
            .|.|:...||:.:::|:|||..|:.|.||||||:.|....||::|:||.|...||||.:||||||
Frog   285 RYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSF 349

  Fly   350 NVPWEKIRECSLDVMVMDFDNIGRNELIGRILLAGKNGSGASETKHWQDMISKPRQTVVQWHRLK 414
            .||:|:|::..:.|.|:|:|.||:|:.||::.: |.|.:|| |.:||.||::.||:.:.|||.|.
Frog   350 EVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFV-GYNSTGA-ELRHWSDMLANPRRPIAQWHTLT 412

  Fly   415 PE 416
            ||
Frog   413 PE 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syt7	NP_726557.3	C2A_Synaptotagmin-7	147..271	CDD:176032	59/123 (48%)
Syt7	NP_726557.3	C2B_Synaptotagmin-7	277..414	CDD:176050	63/136 (46%)
syt1	XP_017947750.1	C2A_Synaptotagmin-1-5-6-9-10	145..268	CDD:176031	59/123 (48%)
syt1	XP_017947750.1	C2B_Synaptotagmin-1	277..412	CDD:176047	63/136 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D394604at33208
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920