Protein Alignment NfI and nfia

DIOPT Version :9

• Sequence 1: NP_995592.2
• Gene: NfI / 43782
• FlyBaseID: FBgn0042696
• Length: 766
• Species: Drosophila melanogaster
• Sequence 2: XP_009294511.1
• Gene: nfia / 556665
• ZFINID: ZDB-GENE-050208-501
• Length: 587
• Species: Danio rerio
• Alignment Length: 694
• Identity: 245/694 - (35%)
• Similarity: 308/694 - (44%)
• Gaps: 216/694 - (31%)

  Fly    28 DEFHPFIEALLPYVKSFSYSWFNLQAAKRKYYKKHEKRMSLEEERHCKDELQNEKTEVKQKWASR 92
            ||||||||||||:|::|:|:||||||.||||:||||||||.||||..||||.:||.|||||||||
Zfish    33 DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQKWASR 97

  Fly    93 LLGKLRKDITQESREDFVQSIIGKRKSICVLSNPDQKGKMRRIDCLRQADKVWRLDLVMVILFKA 157
            ||.||||||..|.|||||.::.||:...||||||||||||||||||||||||||||||||||||.
Zfish    98 LLAKLRKDIRPEFREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRLDLVMVILFKG 162

  Fly   158 IPLESTDGERLEKNPECLHPGLCVNPYHINVSVRELDLYLANFINTHNSINNTNTTFSTTPGVRS 222
            |||||||||||.|:|:|.:|||||.|:||.|||:|||||||.|::..
Zfish   163 IPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAE------------------ 209

  Fly   223 PHITMYNRSNDPNRKDEVADMKNDVVKQNPYNG-VVCNDIILATGVFSSQELWTLSKDLILDESN 286
                 ..:|:.||:..|     .| :|..|.|| :...|..:.:|||:..||..:|:       .
Zfish   210 -----AGQSDSPNQPSE-----GD-IKDQPENGHLGFQDSFVTSGVFTVSELVRVSQ-------T 256

  Fly   287 DINLNSSLIKRENVGATYECNTYQINSESSISAAQSLVQSGSIAANPIPLGYSIDFIDQRITQLS 351
            ..::.|..:|.            |..:.||         |..|||...| .:|:..:|.. :..|
Zfish   257 GPHIKSDTVKP------------QFGTPSS---------SAPIAAGTGP-NFSLADLDSS-SYYS 298

  Fly   352 QS------PLPRTEGPNGDSHDANKI----DQSSSP----------------------------- 377
            .|      |||.|    ..|..|.:|    |:..||
Zfish   299 MSPGAMRRPLPST----SSSSSAKRIKCMEDEVDSPGEESYYPGQGRSPGSGSQASSWHEVEPAG 359

  Fly   378 -----------------PITSTASDNGTSSFSLIVRATDSSIEDPKTSPISLHRYTSLSSRTLAQ 425
                             |..:|...:..|.||..|.:..:|   |:|:....||......|....
Zfish   360 YKLRGSLASSFISRQGMPSPTTLKKSEKSGFSSPVPSQTAS---PRTAFTHHHRPVITGPRASPH 421

  Fly   426 ALPQHSCSLLHSSSTSPTNTL------YYPQHNNTRPSQTTSVEEQNRVGSDKYSTEPQD-ISDF 483
            |.|    |.||    .||:.:      |:..|                  :.:|  .||: :.:|
Zfish   422 ATP----SSLH----FPTSPIIQQPGSYFSHH------------------AIRY--HPQETLKEF 458

  Fly   484 VTYVCQDTSHTTTITGSAENHSFQHSHTLPQGHGHSPHFQIHQQLRSAKLTTSPSTHYHSTML-P 547
            |..||.|:.......|      |.:.:...||..|:|...                   :.|| |
Zfish   459 VQLVCPDSGQQAGQVG------FLNPNGSSQGKVHNPFLP-------------------TPMLPP 498

  Fly   548 PMLPPMARPVAIIRSSSDLTLVQSPPTSLPL-------TAQSTSLNDNSCIAKHSLPTDNRLASN 605
            |..|||||||       .|.:..|.|.|...       |:.|..|  .||:..|.:|     .:.
Zfish   499 PPPPPMARPV-------PLPVPDSKPPSTSTDGGGNSPTSPSECL--TSCMTSHLMP-----HTT 549

  Fly   606 LDNRNSPNNTDVVSQHEMTGTASPQ----PQSHTPTLASPQSYL 645
            |....|..:|....:....|...|.    ||       .||.||
Zfish   550 LTKAYSTPSTSPAQRFVSVGPRDPSFVNIPQ-------QPQWYL 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NfI	NP_995592.2	NfI_DNAbd_pre-N	25..64	CDD:287494	28/35 (80%)
		MH1	85..193	CDD:260161	85/107 (79%)
nfia	XP_009294511.1	NfI_DNAbd_pre-N	32..69	CDD:287494	28/35 (80%)
		MH1	91..195	CDD:260161	82/103 (80%)
		CTF_NFI	236..586	CDD:279231	97/460 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596287
Domainoid	1	1.000	170	1.000	Domainoid score	I3729
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	296	1.000	Inparanoid score	I2723
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D411112at33208
OrthoFinder	1	1.000	-	-		FOG0000997
OrthoInspector	1	1.000	-	-		otm25161
orthoMCL	1	0.900	-	-		OOG6_106071
Panther	1	1.100	-	-	LDO	PTHR11492
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3993
SonicParanoid	1	1.000	-	-		X590
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.930