Protein Alignment NfI and Nfib

DIOPT Version :9

• Sequence 1: NP_995592.2
• Gene: NfI / 43782
• FlyBaseID: FBgn0042696
• Length: 766
• Species: Drosophila melanogaster
• Sequence 2: NP_001106680.1
• Gene: Nfib / 18028
• MGIID: 103188
• Length: 570
• Species: Mus musculus
• Alignment Length: 627
• Identity: 221/627 - (35%)
• Similarity: 291/627 - (46%)
• Gaps: 146/627 - (23%)

  Fly    27 QDEFHPFIEALLPYVKSFSYSWFNLQAAKRKYYKKHEKRMSLEEERHCKDELQNEKTEVKQKWAS 91
            |||||||||||||:|::.:|:||||||.||||:||||||||.:|||..||||.:||.|:||||||
Mouse    10 QDEFHPFIEALLPHVRAIAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLSEKPEIKQKWAS 74

  Fly    92 RLLGKLRKDITQESREDFVQSIIGKRKSICVLSNPDQKGKMRRIDCLRQADKVWRLDLVMVILFK 156
            |||.||||||.||.|||||.::.||:...|||||||||||:||||||||||||||||||||||||
Mouse    75 RLLAKLRKDIRQEYREDFVLTVTGKKHPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFK 139

  Fly   157 AIPLESTDGERLEKNPECLHPGLCVNPYHINVSVRELDLYLANFINTHNSINNTNTTFSTTPGVR 221
            .|||||||||||.|:|.|.:|.|||.|:||.|||:||||:||.::...:|
Mouse   140 GIPLESTDGERLMKSPHCTNPALCVQPHHITVSVKELDLFLAYYVQEQDS--------------- 189

  Fly   222 SPHITMYNRSNDPNRKDEVADMKNDVVKQNPYNGVVCNDIILATGVFSSQELWTLSKDLILDESN 286
                   .:|..|:..|..         :||..  ...|..:.:|||:..||..:|:..| .:..
Mouse   190 -------GQSGSPSHSDPA---------KNPPG--YLEDSFVKSGVFNVSELVRVSRTPI-TQGT 235

  Fly   287 DINLNSSLIKRENVGATYECNTYQINSESSISAAQSLVQSGSIAAN----PIPLGYSIDFIDQRI 347
            .:|.....|..:   ..|......:|.:.|:|:..|..:..:|:.:    |.|.|   ||
Mouse   236 GVNFPIGEIPSQ---PYYHDMNSGVNLQRSLSSPPSSKRPKTISIDENMEPSPTG---DF----- 289

  Fly   348 TQLSQSPLPRTEGPNGDSHDANKIDQSSSPPITSTASDNGTSSFSLIVRATDSSIEDPKTSPISL 412
                   .|....|...|...::.||..|.|.|....:....|      :|......|:.|....
Mouse   290 -------YPSPNSPAAGSRTWHERDQDMSSPTTMKKPEKPLFS------STSPQDSSPRLSTFPQ 341

  Fly   413 HR--------YTSLSSRT--LAQALPQHSCSLLHSSSTSPTN--TLYYPQHNNTR-------PSQ 458
            |.        ::.:|:||  ....||..:.::|..:.:|..:  |:.||.|.|.:       ||.
Mouse   342 HHHPGIPGVAHSVISTRTPPPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSY 406

  Fly   459 TTSVEEQNRVGSDKY---------------STEPQDISDFVTYVCQDTSHTTTITGSAENHSFQH 508
            ..|..:.::..|...               |..|..:.. ||....||...||   |.|..:...
Mouse   407 DPSSPQTSQPNSSGQVVGKVPGHFTPVLAPSPHPSAVRP-VTLTMTDTKPITT---STEGEAASP 467

  Fly   509 SHTLPQGHGHS------------PHFQIHQQLRSAKLTTSPSTHYHSTMLPPMLPPMARPVAIIR 561
            :.|.....|.|            |.|...||||....|.:.:..:                 :..
Mouse   468 TATTYTASGTSQANRYVGLSPRDPSFLHQQQLRICDWTMNQNGRH-----------------LYP 515

  Fly   562 SSSDLTL---VQSPPT--------------SLPLTAQSTSLN 586
            |:|:.||   .|||.|              .||...|:..||
Mouse   516 STSEDTLGITWQSPGTWASLVPFQVSNRTPILPANVQNYGLN 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NfI	NP_995592.2	NfI_DNAbd_pre-N	25..64	CDD:287494	28/36 (78%)
		MH1	85..193	CDD:260161	83/107 (78%)
Nfib	NP_001106680.1	NfI_DNAbd_pre-N	10..47	CDD:313701	28/36 (78%)
		MH1	69..173	CDD:320734	81/103 (79%)
		CTF_NFI	209..498	CDD:307142	65/317 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	252..446		41/215 (19%)
		9aaTAD. /evidence=ECO:0000250|UniProtKB:O00712	397..405		0/7 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	455..474		5/21 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850368
Domainoid	1	1.000	170	1.000	Domainoid score	I3756
eggNOG	1	0.900	-	-		E1_KOG3663
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	296	1.000	Inparanoid score	I2716
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D411112at33208
OrthoFinder	1	1.000	-	-		FOG0000997
OrthoInspector	1	1.000	-	-		otm43933
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11492
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X590
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.950